Search our Database of Scientific Publications and Authors

I’m looking for a
    Spontaneous Coronary Artery Dissection: A Review of Pathogenesis, Presentations, Treatment, and Outcomes.
    • Authors:
    • Aasim Afzal
      Baylor University Medical Center at Dallas
      Syed Sarmast
      Baylor University Medical Center at Dallas and Baylor Hamilton Heart and Vascular Hospital; and Texas A&M College of Medicine (Schussler); and the University of Texas at Austin (Weber)
      James W Choi
      Baylor University Medical Center
      United States
      Peter A McCullough
      Providence Park Heart Institute
      United States
      Jeffrey M Schussler
      Baylor University Medical Center
      United States
    Rev Cardiovasc Med 2017 ;18(1):29-36
    Baylor University Medical Center, Division of Cardiology, Dallas, TX; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX; Texas A&M College of Medicine, Bryan, TX.
    Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndromes and sudden cardiac death. The epidemiology, pathogenesis, and optimal approaches to diagnosis and management are poorly understood. Additionally, SCAD as a syndrome is commonly under-recognized and its prognosis is not well studied. Guidelines on management of SCAD have not yet been established. We present three cases of SCAD that varied in their clinical presentation and describe the different management strategies utilized. This is followed by a review of the clinical features, epidemiology, prognosis, and potential treatment strategies for patients presenting with SCAD.

    Similar Publications

    Spontaneous coronary artery dissection-A review.
    Cardiovasc Diagn Ther 2015 Feb;5(1):37-48
    Division of Cardiology, Vancouver General Hospital, University of British Columbia, Vancouver, BC V5Z1M9, Canada.
    Spontaneous coronary artery dissection (SCAD) is an infrequent and often missed diagnosis among patients presenting with acute coronary syndrome (ACS). Unfortunately, SCAD can result in significant morbidities such as myocardial ischemia and infarction, ventricular arrhythmias and sudden cardiac death. Lack of angiographic recognition from clinicians is a major factor of under-diagnosis. Read More
    Spontaneous dissections of coronary arteries and acute coronary syndromes: rationale and design of the DISCOVERY, a multicenter prospective registry with a case-control group.
    J Cardiovasc Med (Hagerstown) 2009 Jan;10(1):94-9
    Cardiology Unit, Department of Cardiovascular Medicine, S. Bortolo Hospital, Viale Rodolfi 37, 36100 Vicenza, Italy.
    Background: Spontaneous coronary artery dissection (SCAD) is an unusual cause of acute myocardial ischemia that in almost 50% of cases is followed by sudden death. The increasing frequency of SCAD diagnosis may reflect the widespread use of coronary angiography and percutaneous coronary interventions in acute coronary syndromes (ACS). The incidence of SCAD is estimated between 0. Read More
    Clinical features, management, and prognosis of spontaneous coronary artery dissection.
    Circulation 2012 Jul 16;126(5):579-88. Epub 2012 Jul 16.
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA.
    Background: Spontaneous coronary artery dissection (SCAD) is an acute coronary event of uncertain origin. Clinical features and prognosis remain insufficiently characterized.

    Methods And Results: A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Read More
    Spontaneous coronary artery dissection, challenges of diagnosis and management.
    Future Cardiol 2017 Nov 24;13(6):539-549. Epub 2017 Oct 24.
    Cardiology Department, University Hospital Limerick, Limerick, Ireland.
    Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome in young patients. No clear factors exist to predict the natural history of the disease and the prognosis of the condition. Furthermore, current management practice of SCAD is based mainly on retrospective data and case series and clear management guidelines are lacking. Read More