J Psychiatr Pract 2017 May;23(3):191-199
FRYML, WILLIAMS, PELIC, FOX, SAHLEM, ROBERT, and SHORT: Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC REVUELTA: Department of Neurology and Neurosciences, Medical University of South Carolina, Charleston, SC.
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Pharmacotherapy 1986 Jul-Aug;6(4):193-5
Catatonic reactions to high-potency neuroleptic drugs have been described in the literature. Our patient developed neuroleptic-induced catatonia (NIC) after abrupt withdrawal of amantadine, a dopaminergic agent that has been implicated in neuroleptic malignant syndrome (NMS) on its discontinuation. This case report adds support to the hypothesis that NIC and NMS are 2 syndromes on a continuum of dopamine blockade, each of which may be treated with or uncovered by amantadine therapy. Read More
Am J Psychiatry 1994 Mar;151(3):451-2
Minerva Psichiatr 1992 Oct-Dec;33(4):259-83
Istituto di Psichiatria P. Ottonello, Università degli Studi di Bologna.
Neuroleptic malignant syndrome is characterised by muscular rigidity, fever and signs of severe vegetative nervous system involvement. Its etiopathogenesis is still unclear and the disease is potentially fatal. Its clinical aspects, which are often only partially manifested, make it difficult to formulate a correct diagnosis in time, not least due to the problem of differential diagnosis with other syndromes with similar symptoms but a different pathogenesis, psychopathology and therapy: acute lethal catatonia, fatal acute delirium, heat-stroke, malignant hyperthermia. Read More
Ann Clin Psychiatry 2007 Jan-Mar;19(1):9-16
Graylands Hospital and School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia.
Background: This case series study examines the hypothesis that neuroleptic malignant syndrome (NMS) is a heterogeneous condition including catatonic variants and non-catatonic pathological reactions to antipsychotics.
Methods: Fourteen episodes of NMS were prospectively identified. Patients were examined for catatonia during the course of NMS. Read More