Search our Database of Scientific Publications and Authors

I’m looking for a
    Genotype 1 of human parvovirus B19 in clinical cases.
    Rev Assoc Med Bras (1992) 2017 Mar;63(3):224-228
    PhD, Scientific Researcher, Núcleo de Doenças Respiratórias, Instituto Adolfo Lutz, São Paulo, SP, Brazil.
    Introduction:: Virus surveillance strategies and genetic characterization of human parvovirus B19 (B19V) are important tools for regional and global control of viral outbreak. In São Paulo, Brazil, we performed a study of B19V by monitoring the spread of this virus, which is an infectious agent and could be mistakenly reported as a rash and other types of infection.

    Method:: Serum samples were subjected to enzyme immunoassay, real time polymerase chain reaction, and sequencing.

    Results:: From the 462 patients with suspected cases of exanthematic infections, the results of the 164 serum samples were positive for B19V immunoglobulin M. Among these cases, there were 38 patients with erythema infections and B19-associated with other infections such as encephalitis, hydrops fetalis, chronic anemia, hematological malignancies. These samples were sequenced and identified as genotype 1.

    Conclusion:: This study showed patients with infections caused by B19V and sequencing genotype 1. Continuous monitoring is necessary to detect all known genotypes, and the emergence of new genotypes of these viruses for case management in public health control activities.

    Similar Publications

    Prevalence and genotypic characterization of Human Parvovirus B19 in children with measles- and rubella-like illness in Iran.
    J Med Virol 2016 Jun 13;88(6):947-53. Epub 2015 Nov 13.
    Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Human Parvovirus B19 (B19V) is a prototype of the Erythroparvovirus genus in Parvoviridae family. B19V infections are often associated with fever and rash, and can be mistakenly reported as measles or rubella. Differential diagnosis of B19V illness is necessary for case management and also for public health control activities, particularly in outbreak situations in which measles or rubella is suspected. Read More
    Insights into epidemiology of human parvovirus B19 and detection of an unusual genotype 2 variant, Bulgaria, 2004 to 2013.
    Euro Surveill 2016 ;21(4)
    National Center of Infectious and Parasitic Diseases, Department Virology, National Reference Laboratory of Measles, Mumps and Rubella, Sofia, Bulgaria.
    The present study aimed to determine the role of human parvovirus В19 (B19V) as an aetiological agent in measles and rubella negative fever/rash patients from Bulgaria between 2004 and 2013. A total of 1,266 sera from all over the country were tested for B19V IgM antibodies and all positives were further investigated by polymerase chain reaction (PCR). Overall, 280 sera (22%) were B19V IgM positive and 227 of these (81%) were also PCR positive. Read More
    Prevalence and genotypic characterization of human parvovirus B19 in children with hemato-oncological disorders in North India.
    J Med Virol 2015 Feb 2;87(2):303-9. Epub 2014 Aug 2.
    Department of Microbiology, King George's Medical University, Lucknow, India.
    Human parvovirus B19 (B19V) has been associated with chronic anemia in immuno-compromised patients. In the present study, the prevalence and genotype distribution of B19V in children from North India, suffering with hemato-oncological disorders is reported. Children with aplastic anemia/leukemia/chronic hematological disorders, and healthy blood donors were enrolled in the study. Read More
    Quantitation of human parvovirus B19 DNA in erythema infectiosum and aplastic crisis.
    J Med Virol 2014 Dec 24;86(12):2102-6. Epub 2014 Jun 24.
    Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan.
    Several publications concerning the methods of real-time PCR for human parvovirus B19 (B19V) have appeared and some case reports mention B19V DNA loads. However, no large-scale study quantitating levels of B19V DNA in common or representative B19V manifestations such as erythema infectiosum and aplastic crisis has been performed. Consequently, using the TaqMan PCR assay, the B19V load in a large sample of subjects with erythema infectiosum or aplastic crisis was quantitated. Read More