Ann Thorac Med 2017 Apr-Jun;12(2):101-106
Department of Medicine, King Saud University, Riyadh, Saudi Arabia.
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Am J Med 1996 Sep;101(3):262-9
Department of Medicine, Columbia-Presbyterian Medical Center, New York, New York 10032, USA.
Purpose: Fractures, a common complication of cardiac and liver transplantation, have not been reported in association with lung transplantation. However, many patients with end-stage pulmonary disease have multiple risk factors for osteoporosis, and several studies have suggested that osteoporosis before transplantation may increase the risk of fracture after transplantation. Therefore, we evaluated a group of patients with end-stage pulmonary disease who were awaiting lung transplantation to determine the prevalence of osteoporosis. Read More
COPD 2012 Aug 11;9(4):332-7. Epub 2012 Apr 11.
Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Bone mineral density (BMD) alone does not reliably predict osteoporotic fractures. The Fracture Risk Assessment Tool (FRAX) was developed to estimate the risk of fracture in the general population. This study was designed to identify predictors of osteoporosis and vertebral fractures in patients presenting with chronic obstructive pulmonary disease (COPD). Read More
Respir Res 2011 Dec 16;12:157. Epub 2011 Dec 16.
Department of Respiratory Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Background: Osteoporosis is one of the systemic features of COPD. A correlation between the emphysema phenotype of COPD and reduced bone mineral density (BMD) is suggested by some studies, however, the mechanisms underlying this relationship are unclear. Experimental studies indicate that IL-1β, IL-6 and TNF-α may play important roles in the etiology of both osteoporosis and emphysema. Read More
Bone 2012 Jun 9;50(6):1234-9. Epub 2012 Mar 9.
Department of Respiratory Medicine, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
The prevalence of osteoporosis is high in chronic obstructive pulmonary disease (COPD) patients. The gold standard for the diagnosis of osteoporosis is bone mineral density (BMD) measurements as assessed by dual energy absorptiometry (DXA) scanning as well as vertebral fractures as assessed by instant vertebral assessment (IVA). The aim of this study was to compare COPD GOLD II patients (that is, patients with moderate COPD, stage II, according to the GOLD classification) with osteoporosis (cases) to COPD GOLD II patients without osteoporosis (controls) to identify risk factors for osteoporosis. Read More