Insulin Degludec 200 Units/mL Is Associated With Lower Injection Frequency and Improved Patient-Reported Outcomes Compared With Insulin Glargine 100 Units/mL in Patients With Type 2 Diabetes Requiring High-Dose Insulin.

Authors:
Mark L Warren
Mark L Warren
Physicians East
Fort Dodge | United States
Serge Jabbour
Serge Jabbour
Thomas Jefferson University
United States
Charlotte T Hansen
Charlotte T Hansen
Odense University Hospital
Dr Paul Norwood, MD
Dr Paul Norwood, MD
University of California at San Francisco
Associate Clinical Professor of Medicine at UC San Francisco
Diabetes, cholesterol, hypertension,
Fresno, CA | United States

Clin Diabetes 2017 Apr;35(2):90-95

Valley Research, Fresno, CA.

Many patients with type 2 diabetes require high basal insulin doses, necessitating multiple injections, increasing patient burden, and resulting in reduced treatment adherence. This randomized, controlled, crossover trial compared the efficacy, safety, and patient-reported outcomes for a concentrated formulation of insulin degludec (200 units/mL) to those of insulin glargine in patients requiring high doses of basal insulin. By offering equivalent glycemic control while reducing the rate of confirmed hypoglycemia and the number of injections required for administration, insulin degludec 200 units/mL may be preferred by patients with type 2 diabetes who require high basal insulin doses.

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Source
http://clinical.diabetesjournals.org/lookup/doi/10.2337/cd15
Publisher Site
http://dx.doi.org/10.2337/cd15-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391813PMC

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April 2017
22 Reads
2 Citations

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