J Dermatol 2018 Jan 2;45(1):109-110. Epub 2017 Feb 2.
Department of Dermatology, Kansai Medical University, Hirakata, Japan.
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J Invest Dermatol 1999 Jul;113(1):4-10
Dermatology, University AZU, Utrecht, The Netherlands.
After ultraviolet exposure Langerhans cells (epidermal CD1a+ cells) disappear from the healthy skin, and CD11b+ macrophage-like cells, which are reported to produce interleukin-10, appear in a matter of days. These phenomena are related to the ultraviolet-induced local suppression of contact hypersensitivity reactions. A defect in this suppression might allow inadvertent immune reactions to develop after ultraviolet (over)exposure; i. Read More
Photodermatol Photoimmunol Photomed 1994 Aug;10(4):139-43
Department of Dermatology, Karolinska Hospital, Stockholm, Sweden.
Twenty-two patients with polymorphous light eruption were prophylactically treated with ultraviolet A (UVA) with and without trimethylpsoralen in the first randomized double-blind study in this subject. Twelve of the patients were treated during 2 consecutive springs with placebo during one spring and psoralens during the other. Eighteen of the patients improved after the therapy, but there was no clear-cut difference between the 2 regimens. Read More
Photodermatol Photoimmunol Photomed 2013 Feb;29(1):52-4
Department of Dermatology and Skin Science, University of British Columbia, Photomedicine Institute, Vancouver Costal Health Research Institute, Vancouver, British Columbia, Canada.
Polymorphous light eruption (PMLE) is the most common photodermatosis and is characterized by the development of a pruritic skin eruption within a few hours to days after sun or artificial light exposure. The eruption usually takes up to two weeks to resolve in the absence of further ultraviolet radiation. PMLE has been reported as a side effect of ultraviolet A1 (UVA1) therapy but characteristics of the eruption, especially the duration until resolution after treatment, has not been described. Read More
Photodermatol Photoimmunol Photomed 2008 Jun;24(3):155-61
Department of Dermatology, Medical University of Vienna, Vienna, Austria.
Polymorphous light eruption is the most common photodermatosis, with a prevalence of as high as 10-20% in Western Europe and in the USA. It starts during the second and third decades of life. Although not life-threatening it can severely impair the quality of life, in particular during leisure activities and in outdoors workers. Read More