Tenosynovitis caused by Scedosporium apiospermum infection misdiagnosed as an Alternaria species: a case report.

Authors:
Sung-Chul Lim
Sung-Chul Lim
Chosun University
South Korea
JoA Kim
JoA Kim
Chosun University Hospital
Dong-Min Kim
Dong-Min Kim
Chosun University College of Medicine
South Korea
Piyush Jha
Piyush Jha
School of Medicine

BMC Infect Dis 2017 01 14;17(1):72. Epub 2017 Jan 14.

Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.

Background: Scedosporium apiospermum, which can usually be isolated from soil, polluted stream water and decaying vegetation, is increasingly recognized as an opportunistic dematiaceous fungus. The mortality rate of infection in immunocompromised hosts is over 50%. S. apiospermum is commonly responsible for dermal and epidermal infections (i.e., mycetoma) after traumatic penetration.

Case Presentation: A 73-year-old woman was admitted to our hospital complaining of painful swelling and tenderness on the dorsum of the proximal left wrist and hand. The symptoms had persisted for approximately 2 months. A physical examination revealed a 4 x 3 cm, poorly defined, erythematous papule, which was fluctuant, with pustules and crusts on the dorsum of the left hand.

Conclusions: We report a very rare case of tenosynovitis caused by S. apiospermum infection. We identified the infectious agent via molecular DNA sequencing. The infectious agent was initially misidentified as an Alternaria species by microscopic examination with lactophenol cotton blue (LPCB) staining. The infection was successfully treated with debridement and adjuvant fluconazole therapy.

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Source
http://dx.doi.org/10.1186/s12879-016-2098-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237512PMC

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January 2017
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References

(Supplied by CrossRef)
Article in Arch Neurol
P Kershaw et al.
Arch Neurol 1990
Article in Clin Infect Dis
S Husain et al.
Clin Infect Dis 2003
Article in Clin Infect Dis
S Husain et al.
Clin Infect Dis 2005
Article in Medicine
B Castiglioni et al.
Medicine 2002
Article in Clin Infect Dis
MN Kim et al.
Clin Infect Dis 2009
Article in Clin Infect Dis
GA Lamaris et al.
Clin Infect Dis 2006
Article in J Nephrol
B Gallelli et al.
J Nephrol 2006
Article in Asian J Surg
CC Hsu et al.
Asian J Surg 2015
Article in Clin Microbiol Infect
FJ Pastor et al.
Clin Microbiol Infect 2008
Article in J Clin Rheumatol
GMF Ruinemans et al.
J Clin Rheumatol 2011
Article in Korean J Med Mycol
JH Ko et al.
Korean J Med Mycol 2010

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