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Bioresour Technol 2021 Feb 27;329:124905. Epub 2021 Feb 27.

Department of Civil and Environmental Engineering, Hanyang University, Seongdong-gu, Seoul 04763, Republic of Korea. Electronic address:

Parameters of temperature-phased anaerobic digestion (TPAD) were varied to study their effects on hydrolysis, biomethane potential (BMP), and microbial diversity of microalgae biodegradation. Anaerobic pretreatments at 85 °C demonstrated the release of soluble carbohydrate and protein molecules under low microbial metabolic activity. However, at 55 °C, anaerobic pretreatments showed superior performance in methane yield, nutrient release, and volatile fatty acids (VFAs) production due to dominant Clostridium. Read More

Poult Sci 2021 Jan 23;100(4):101014. Epub 2021 Jan 23.

College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, China; Ministry of Education Engineering Research Center of Feed Safety and Efficient Use, Changsha, Hunan, China; Hunan Engineering Research Center of Poultry Production Safety, Changsha, Hunan, China; Hunan Co-Innovation Center of Animal Production Safety, Changsha, Hunan, China.

The chicken egg yolk, which is abundant with lipids, proteins, and minerals, is the major nutrient resource for the embryonic development. In fact, the magnitude and type of yolk nutrients are dynamically changed during the chicken embryogenesis to meet the developmental and nutritional requests at different stages. The yolk nutrients are metabolized and absorbed by the yolk sac membrane and then used by the embryo or other extraembryonic tissues. Read More

Mol Metab 2021 Mar 3:101202. Epub 2021 Mar 3.

Department of Cellular and Molecular Function Analysis, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan. Electronic address:

Objective: The impairment of circadian clocks is a cause of obesity, but the pathophysiological role of the circadian clock in brown adipose tissue (BAT), a major tissue regulating energy metabolism, remains unclear. To address this issue, we investigated the effects of complete disruption of the BAT clock on thermogenesis and energy expenditure.

Methods: The mice with brown adipocyte-specific knockout of the core clock gene Bmal1 (BA-Bmal1 KO) were generated and analyzed. Read More

Fungal Genet Biol 2021 Mar 3:103550. Epub 2021 Mar 3.

Amity Institute of Integrative Science and Health and Amity Institute of Biotechnology, Amity University Gurgaon, Haryana, India. Electronic address:

The ATP binding cassette (ABC) transporters, first discovered as high-affinity nutrient importers in bacteria, rose to prominence when their ability to confer multidrug resistance (MDR) to cancer cells was realized. The most characterized human permeability glycoprotein (P-gp) is a dominant exporter of anti-cancer drugs and its overexpression is directly linked to MDR. The overexpression of drug efflux pumps belonging to the ABC superfamily is also a frequent cause of resistance to antifungals. Read More

Neurosci Biobehav Rev 2021 Mar 3. Epub 2021 Mar 3.

Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland; APC Microbiome Institute, University College Cork, Cork, Ireland. Electronic address:

There is increasing knowledge regarding the role of the microbiome in modulating brain and behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain communication in humans. Among these metabolites short-chain fatty acids, tryptophan, and bile acid metabolites/pathways show strong preclinical evidence for involvement in various aspects of brain function and behaviour. Read More