Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy.

Neuroophthalmology 2015 Oct 24;39(5):240-242. Epub 2015 Aug 24.

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis , St. Louis, Missouri, USA.

Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.

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Source
http://dx.doi.org/10.3109/01658107.2015.1059464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123132PMC
October 2015

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