Ofuji disease: a rare dermatosis and its challenging therapeutic approach.

An Bras Dermatol 2016 Sep-Oct;91(5):646-648

Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.

Eosinophilic pustular folliculitis (EPF) or Ofuji disease is a rare dermatosis, prone to recurrence and chronicity. The peak incidence occurs in the third decade of life and its exact etiology remains unknown. Evidence suggests that the expression of adhesion molecules and the production of cytokines activate the follicular unit, but the stimulus that triggers these changes remains unclear. The three clinical variants reported in the literature include classic EPF, immunosuppression-associated EPF, and infancy-associated EPF. We report a case of eosinophilic pustular folliculitis with peculiar epidemiological characteristics, which represents a challenging therapeutic scenario.

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http://dx.doi.org/10.1590/abd1806-4841.20164778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087226PMC

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May 2017
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