Jpn J Radiol 2017 Jan 7;35(1):31-39. Epub 2016 Nov 7.
Department of Medical Imaging, The First Affiliated Hospital, Kunming Medical University, 295 Xichang Road, Kunming, Yunnan, 650032, People's Republic of China.
Purpose: To investigate in vivo effect of radiofrequency ablation (RFA) on swine long bones and the repair process.
Materials And Methods: RFA was performed in six swine at the end and middle part of the tibia or femur. After RFA, radiological examinations were performed, and the swine were killed immediately and at different time points post-RFA for histopathological examination.
Results: All swine had successful RFA. The RFA-induced elliptical necrotic area ranged from 3.81-5.24 cm (mean 4.08 ± 0.73 cm) at the bone end but 5.60-8.98 cm (mean 7.58 ± 1.41) at the middle part immediately after RFA until 10 days, with the necrosis area significantly smaller (P = 0.000) at the end than at the middle. RFA only damaged the cortical bone slightly (0.01 cm thick) with no damage to the soft tissues outside the compact bone at both the end and middle. Surrounding the elliptic pale zone of coagulative necrosis was a narrow brown band of hemorrhage and inflammatory exudate. From day 10 until week 12, tissue proliferation and repair became increasingly apparent, with proliferated granulation, fibrous tissue, and fresh and mature bone trabecula.
Conclusion: RFA can quickly and effectively destroy the cancellous bone tissue without affecting the cortical bone and activate bone remodeling.
We have submitted your request - we will update you on status within the next 48 hours.
Sign up for further access to Scientific Publications and Authors!
What are PubFacts Points?
PubFacts points are rewards to PubFacts members, which allow you to better promote your profile and articles throughout PubFacts.com
How do I earn PubFacts Points?
Each member is given 50 PubFacts points upon signing up. You can earn additional points by completing 100% of your profile, creating and participating in discussions, and sharing other members research.
What can I do with PubFacts Points?
Currently, you can use PubFacts Points to promote and increase readership of your articles.