Dentigerous Cyst and Ameloblastoma of the Jaws.

Int J Surg Pathol 2017 Apr 24;25(2):141-147. Epub 2016 Sep 24.

1 Queen Victoria Hospital NHSF Trust, East Grinstead, West Sussex, UK.

Aim: To determine how many ameloblastomas were misdiagnosed as dentigerous cysts (DCs) by correlating the radiological and histopathological features of a series of both entities.

Methods And Results: Histopathology reports and radiological imaging of 135 DCs and 43 ameloblastomas were reviewed. Any clinical or radiological feature that suggested that the diagnosis of DC was wrong-for example, absence of an unerupted tooth-prompted review of the original histology. A total of 34 cases coded as DC at diagnosis were excluded; in the remaining 101 patients, the clinicoradiological and histopathological features were consistent with DC in 96 (95.0%). Review of the histology revealed that 4 patients had actually had odontogenic keratocysts (OKCs) and one a luminal/simple unicystic ameloblastoma (UA). One other OKC and 3 other ameloblastomas (1 luminal UA, 2 solid/multicystic) had originally been diagnosed as DC; these had been identified prior to the study. Of the 9 misdiagnosed patients, 6 were ≤20 years old. Clinically, DC had been the only, or one of the differential, diagnoses in 7 patients; in the other 2, the clinical diagnosis was radicular cyst. In none of the 4 misdiagnosed ameloblastomas was the radiology compatible with a diagnosis of DC. Incorrect terminology had been used on the histopathology request form in 5 of the 34 excluded cases where the clinical diagnosis was DC, despite the cyst being periapical to an erupted carious or root-filled tooth.

Conclusions: The entire clinical team must ensure that a histopathological diagnosis of DC is consistent with the clinicoradiological scenario, particularly in younger patients.

Download full-text PDF

Source
http://dx.doi.org/10.1177/1066896916666319DOI Listing
April 2017
10 Reads

Publication Analysis

Top Keywords

histopathological features
8
clinical diagnosis
8
diagnosis
6
patients
5
okc ameloblastomas
4
originally diagnosed
4
solid/multicystic originally
4
luminal solid/multicystic
4
diagnosed identified
4
ameloblastomas luminal
4
prior study
4
≤20 years
4
years clinically
4
clinically differential
4
patients ≤20
4
misdiagnosed patients
4
ameloblastoma okc
4
study misdiagnosed
4
identified prior
4
luminal/simple unicystic
4

References

(Supplied by CrossRef)

Churchill HR et al.
Dent Cosmos 1932

Lucas RB et al.
1984

Speight P et al.
2016

Similar Publications