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    Narrowband UVB-induced iatrogenic polymorphous light eruption: a case and suggestions to overcome this rare complication.
    Dermatol Online J 2016 Jun 15;22(6). Epub 2016 Jun 15.
    UCSF Psoriasis and Skin Treatment Center.
    Polymorphous light eruption (PMLE) is the most common photodermatosis characterized by pruritic papules and papulovesicles, which appear hours to days following ultraviolet (UV) exposure. Herein, the authors report successful treatment of generalized plaque psoriasis with Goeckerman regimen in a patient despite new onset iatrogenic PMLE following narrowband (NB) UVB therapy. Although further studies are necessary, this case suggests that the co-existence of psoriasis and PMLE should not prevent the use of phototherapy; phototherapy, especially as part of the Goeckerman regimen, remains a valuable treatment option for psoriasis in patients with PMLE.

    Similar Publications

    Uremic pruritus treated successfully with the Goeckerman Program.
    Dermatol Online J 2016 Aug 15;22(8). Epub 2016 Aug 15.
    Department of Dermatology, University of California San Francisco.
    Uremic pruritus (UP) is a common condition among patients with chronic kidney disease (CKD) on hemodialysis (HD). We report 19 a case of severe UP recalcitrant to conventional therapy including topical corticosteroids, anti-histamines, and phototherapy, 20 which was treated successfully with the Goeckerman regimen consisting of topical coal tar, topical corticosteroids, and broadband 21 UVB (BB-UVB). Little is known about the pathophysiology of UP, and there is currently no consensus or evidence-based 22 treatments for UP. Read More
    Narrow band ultraviolet-B versus Goeckerman therapy for psoriasis with and without acitretin: A retrospective study.
    Indian J Dermatol Venereol Leprol 2015 Nov-Dec;81(6):584-7
    Department of Dermatology, Gülhane School of Medicine, Ankara 06018, Turkey.
    Background: Narrow band ultraviolet-B (NB-UVB) is now one of the most widely used modalities in the treatment of psoriasis. However, despite its high efficacy, conventional Goeckerman treatment has fallen out of favor in recent years and some institutions are now using NBUVB with coal tar as their regimen.

    Objective: To evaluate the efficacy of NB-UVB, Goeckerman therapy and the effect of addition of retinoid to the treatment regimen in the treatment of psoriasis,. Read More
    Persistent polymorphous light eruption after ultraviolet A1 phototherapy.
    Photodermatol Photoimmunol Photomed 2013 Feb;29(1):52-4
    Department of Dermatology and Skin Science, University of British Columbia, Photomedicine Institute, Vancouver Costal Health Research Institute, Vancouver, British Columbia, Canada.
    Polymorphous light eruption (PMLE) is the most common photodermatosis and is characterized by the development of a pruritic skin eruption within a few hours to days after sun or artificial light exposure. The eruption usually takes up to two weeks to resolve in the absence of further ultraviolet radiation. PMLE has been reported as a side effect of ultraviolet A1 (UVA1) therapy but characteristics of the eruption, especially the duration until resolution after treatment, has not been described. Read More
    LCD plus NB-UVB reduces time to improvement of psoriasis vs. NB-UVB alone.
    J Drugs Dermatol 2009 Apr;8(4):351-7
    Psoriasis Treatment Center of Central New Jersey, East Windsor, NJ 08520, USA.
    Background: Use of coal tar with narrowband (NB) ultraviolet B (UVB) light (the Goeckerman regimen) is an effective treatment for plaque psoriasis that has become impractical in outpatient care mainly due to the inconvenience and aesthetic concerns of coal tar.

    Objective: This study evaluated the safety, efficacy, and convenience of adding a novel LCD (coal tar) solution to standard NB-UVB phototherapy in adults with chronic plaque psoriasis.

    Methods: Patients applied LCD solution to half-body twice daily at home and received outpatient full-body NB-UVB light therapy 3 times a week for up to 12 weeks. Read More