Advanced age impacts surgical characteristics and postoperative course in patients with Crohn's disease.

Int J Surg 2016 Sep 13;33 Pt A:182-6. Epub 2016 Aug 13.

Medical University of Vienna, Department of Surgery, Austria.

Purpose: Due to a lack of data, the present study was designed to assess the impact of advanced age on surgical characteristics and short-term outcome of patients operated on for symptomatic Crohn's disease.

Methods: We enrolled 454 consecutive Crohn's disease patients, who underwent intestinal resection at an academic tertiary referral center between 1997 and 2012. Patients were divided into 3 groups according to their age (group I: <30 years, group II: 30-50 years, group III: >50 years) and analyzed retrospectively.

Results: Altogether, 152 (33.5%) patients were included in group I, 234 (51.5%) in group II and 68 (15.0%) in group III. Abscess formation and penetrating disease were significantly more common in younger patients (p = 0.0014 and p = 0.0182). The number of intestinal resections was higher in older patients (p < 0.0001), whereas the laparoscopic approach was more frequently observed in younger adults (p = 0.0006). Group II (n = 58 (24.8%)) and group III (n = 15 (22.1%)) showed significantly more complications compared to group I (n = 20 (13.2%)) (p = 0.0346). Notably, major complications and anastomotic leaks were significantly higher in older patients (p = 0.0004).

Conclusion: Crohn's disease patients of advanced age show different surgical characteristics compared to younger patients and are at an increased risk of developing postoperative complications.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijsu.2016.08.012DOI Listing
September 2016
6 Reads

Publication Analysis

Top Keywords

crohn's disease
8
advanced age
8
surgical characteristics
8
patients
7
tertiary referral
4
formation penetrating
4
diseasemethods enrolled
4
academic tertiary
4
referral center
4
center 1997
4
2012 patients
4
1997 2012
4
abscess formation
4
penetrating disease
4
resection academic
4
disease patients
4
enrolled 454
4
consecutive crohn's
4
454 consecutive
4
patients underwent
4

Similar Publications