J Cutan Pathol 2016 Dec 9;43(12):1102-1111. Epub 2016 Sep 9.
Department of Dermatology, College of Medicine, National Cheng Kung University and Hospital, Tainan, Taiwan.
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Arch Dermatol 2006 May;142(5):587-95
Departments of Dermatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Objectives: To determine the pathogenic association of latent Epstein-Barr virus (EBV) infections with both typical hydroa vacciniforme (HV) and severe HV-like eruptions, and to survey the complications and outcomes of patients.
Design: Case series.
Patients: Twenty-nine patients with HV or severe HV-like eruptions. Read More
Pediatr Dermatol 2010 Sep-Oct;27(5):463-9
Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Hydroa vacciniforme-like cutaneous lymphoma is a rare type of Epstein-Barr virus-associated lymphoma. We analyze clinicopathologic features of seven Chinese child patients with hydroa vacciniforme-like cutaneous lymphoma and determine the pathogenic association of Epstein-Barr virus with this disorder. Clinical, histologic, and immunohistochemical features were reviewed. Read More
Br J Dermatol 2004 Aug;151(2):372-80
Department of Dermatology, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul 110-744, Korea.
Background: There are many reports of patients with a severe hydroa vacciniforme (HV)-like eruption in which cutaneous lesions occur in both sun-exposed and non-exposed areas, unlike in true HV. Several patients have died from a malignant haematological neoplasm. In most cases, a latent Epstein-Barr virus (EBV) infection has been detected in the skin lesions. Read More
Br J Dermatol 1999 Apr;140(4):715-21
Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima 960-1295, USA.
Patients with hydroa vacciniforme (HV)-like eruptions and malignant potential have been reported from Asia and Mexico, and those patients frequently had an associated latent Epstein-Barr virus (EBV) infection. In order to elucidate the association of latent EBV infection with HV, we studied six children with typical manifestations of HV by detection of EBV genes and EBV-related RNAs in biopsy specimens from cutaneous lesions. Cutaneous lesions of all six children with typical HV contained EBV-encoded small nuclear RNA (EBER)+ cells in 3-10% of the dermal infiltrates, whereas no Bam HI-H, l-fragment (BHLF) mRNA, or transcripts encoding EA-D antigen, were detected. Read More