J Neurol Sci 2016 Jul 19;366:18-19. Epub 2016 Apr 19.
Geriatric Department, Memory Clinic Bldg 20, University Hospital Oslo, Oslo University, Oslo, Norway.
Comput Med Imaging Graph 2021 Mar 26;90:101904. Epub 2021 Mar 26.
Shanghai United Imaging Intelligence Co. Ltd, Shanghai, China; School of Biomedical Engineering, ShanghaiTech University, Shanghai, China; Department of Artificial Intelligence, Korea University, Seoul 02841, Republic of Korea. Electronic address:
Medical image registration is a critical process for automated image computing, and ideally, the deformation field from one image to another should be smooth and inverse-consistent in order to bidirectionally align anatomical structures and to preserve their topology. Consistent registration can reduce bias caused by the order of input images, increase robustness, and improve reliability of subsequent quantitative analysis. Rigorous differential geometry constraints have been used in traditional methods to enforce the topological consistency but require comprehensive optimization and are time consuming. Read More
Neuroimage 2021 May 5:118138. Epub 2021 May 5.
Radboud University, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands.
Multi-echo gradient echo (ME-GRE) magnetic resonance signal evolution in white matter has a strong dependence on the orientation of myelinated axons with respect to the main static field. Although analytical solutions have been able to predict some of the white matter (WM) signal behaviour of the hollow cylinder model, it has been shown that realistic models of WM offer a better description of the signal behaviour observed. In this work, we present a pipeline to (i) generate realistic 2D WM models with their microstructure based on real axon morphology with adjustable fiber volume fraction (FVF) and g-ratio. Read More
Metab Brain Dis 2021 May 8. Epub 2021 May 8.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Mucolipidosis type IV (MLIV; OMIM 252,650) is an autosomal recessive lysosomal disorder caused by mutations in MCOLN1. MLIV causes psychomotor impairment and progressive vision loss. The major hallmarks of postnatal brain MRI are hypomyelination and thin corpus callosum. Read More
Eur J Cardiothorac Surg 2021 May 8. Epub 2021 May 8.
South Tees Hospitals NHS Trust, Middlesbrough, UK.
Objectives: The risk of brain injury following surgery for type A aortic dissection (TAAD) remains substantial and no consensus has still been reached on which neuroprotective technique should be preferred. We aimed to investigate the association between neuroprotective strategies and clinical outcomes following TAAD repair.Methods: Using the UK National Adult Cardiac Surgical Audit, we identified 1929 patients undergoing surgery for TAAD (2011-2018). Read More
Nat Methods 2021 May;18(5):459-460
Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.