PLoS One 2016 8;11(6):e0156754. Epub 2016 Jun 8.
Department of Chemistry and Biology, Ryerson University, Toronto, Ontario, Canada.
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Antioxid Redox Signal 2018 Mar 28. Epub 2018 Mar 28.
2 Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine , New York, New York.
Significance: Autophagy, a lysosome-dependent homeostatic process inherent to cells and tissues, has emerging significance in the pathogenesis of human disease. This process enables the degradation and turnover of cytoplasmic substrates via membrane-dependent sequestration in autophagic vesicles (autophagosomes) and subsequent lysosomal delivery of cargo. Recent Advances: Selective forms of autophagy can target specific substrates (e. Read More
J Clin Nurs 2017 Dec 11;26(23-24):5052-5064. Epub 2017 Oct 11.
School of Nursing, Midwifery and Paramedicine, Australian Catholic University, Brisbane, Qld, Australia.
Aims And Objectives: To explore Indigenous people's experiences of hospitalisation for acute cardiac care.
Background: Indigenous Australians suffer a higher burden of cardiovascular ill health and hospitalisation rates in comparison with other Australians, but there is little research that explores their perspectives of hospitalisation.
Design: Narrative inquiry. Read More
Mol Cancer Res 2017 03 5;15(3):281-293. Epub 2017 Jan 5.
UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Prostate cancer is the second most common cancer in men worldwide. Gleason grading is an important predictor of prostate cancer outcomes and is influential in determining patient treatment options. Clinical decisions based on a Gleason score of 7 are difficult as the prognosis for individuals diagnosed with Gleason 4+3 cancer is much worse than for those diagnosed with Gleason 3+4 cancer. Read More
Clin Pract 2016 Oct 24;6(4):865. Epub 2016 Nov 24.
Department of Pediatric Medicine; Topiwala National Medical College and BYL Nair Ch Hospital , Mumbai, Maharashtra, India.
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl transferase and raised serum bile acid levels. His liver biopsy showed bland cholestasis and electron microscopy showed granular bile suggestive of progressive familial intrahepatic cholestasis type I. Read More
Mol Imaging Radionucl Ther 2012 Apr 1;21(1):6-12. Epub 2012 Apr 1.
Karolinska University Hospital Solna, Departments of Radiology and Nuclear Medicine, Solna, Sweden.
Objective: The sensitivity of FDG at PET examination of Hepatocellular Carcinoma (HCC) is restricted. In a few studies, all done in Oriental patients, PET-examination with (11)C-acetate has shown a higher accuracy than with FDG. In the current study, the uptake of (11)C-acetate has been compared with the uptake of FDG in the primary HCC in a cohort of Occidental patients. Read More