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Sci Rep 2021 Feb 9;11(1):3402. Epub 2021 Feb 9.

Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

Ischemic heart disease (IHD) is one of the leading causes of death worldwide. While extreme summer surface air temperatures are thought to be a risk factor for IHD, it is unclear whether large-scale climate patterns also influence this risk. This multi-national population-based study investigated the association between summer Pacific and Atlantic sea surface temperature (SST) variability and annual acute myocardial infarction (AMI) or IHD event rates among older adults residing in North America and the United Kingdom. Read More

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jan 2;245:118900. Epub 2020 Sep 2.

EA 6295 Nano-médicaments and Nano-sondes, Université de Tours, Tours, France.

To demonstrate the potential of Raman spectroscopy for the qualitative and quantitative analysis of solid dosage pharmacological formulations, different concentrations of Sitagliptin, an Active Pharmaceutical Ingredient (API) currently prescribed as an anti-diabetic drug, are characterised. Increase of the API concentrations induces changes in the Raman spectral features specifically associated with the drug and excipients. Principal Component Analysis (PCA) and Partial Least Squares Regression (PLSR), were used for the qualitative and quantitative analysis of the spectral responses. Read More

Diabetes Metab Syndr 2020 Sep - Oct;14(5):1511-1518. Epub 2020 Jul 21.

Department of Physiology College of Medicine Imam Abulrahman Bin Faisal University, Dammam, Saudi Arabia. Electronic address:

Background And Aim: The present study compared cardiovascular autonomic activity and reactivity during fasting (FS) and hyperglycemia (HS) states in young healthy females.

Methods: This case crossover study was conducted on 30 females recruited by convenient sampling. Blood glucose levels were measured in FS and after oral glucose load i. Read More

J Pharm Bioallied Sci 2020 Apr-Jun;12(2):102-111. Epub 2020 Apr 10.

Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, UAE.

Objective: The aim of this systematic review was to evaluate the clinical implications of continuous glucose monitoring (CGM) among patients with diabetes mellitus using variables that include glycated hemoglobin (HbA1c), estimated A1c, glucose variability, and users' perspectives.

Materials And Methods: This study analyzed 17 articles that were identified and studied according to the research question criteria. PRISMA guidelines were used for identification and screening of the literature. Read More

Lancet Respir Med 2020 06;8(6):585-596

Background: Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the burden of chronic respiratory diseases globally, providing a comprehensive and up-to-date analysis on geographical and time trends from 1990 to 2017.

Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017, we estimated the prevalence, morbidity, and mortality attributable to chronic respiratory diseases through an analysis of deaths, disability-adjusted life-years (DALYs), and years of life lost (YLL) by GBD super-region, from 1990 to 2017, stratified by age and sex. Read More