Rom J Intern Med 2016 Jan-Mar;54(1):66-9
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Indian J Pathol Microbiol 2013 Oct-Dec;56(4):355-8
Department of pathology, K. J. Somaiya Medical College and Research Centre, Mumbai, Maharashtra, India.
Background: Perforating disorders of the skin, is an often overlooked entity characterized by transepidermal elimination of material from the upper dermis and are classified histopathologically according to the type of epidermal disruption and the nature of the eliminated material. They include Kyrle's disease, perforating folliculitis, reactive perforating collagenosis, and elastosis perforans serpiginosa.
Aim: The aim of this study was to delineate the clinical and histopathological features of perforating disorders of the skin. Read More
BMJ Case Rep 2014 Jan 15;2014. Epub 2014 Jan 15.
Konya Training and Research Hospital, Konya, Turkey.
Kyrle's disease (KD) is a dermatosis which was first described by Kyrle as "hyperkeratosis follicularis et parafollicularis in cutem penetrans" in 1916. Perforating dermatoses are a heterogeneous disorder group characterised by transepithelial elimination. KD has been seen in association with multiple disorders, including diabetes mellitus, renal and liver diseases, congestive heart failure, hyperlipidaemia, infective diseases and abnormal metabolism of vitamin A. Read More
Med Pregl 2002 Jan-Feb;55(1-2):47-50
Klinika za kozno-venericne bolesti, Klinicki centar, Novi Sad.
Introduction: Hyperkeratosis follicularis et parafollicularis in cuten penetrans known as Kyrle's disease is a recessive hereditary genodermatosis. Generally, Kyrle's disease appears between 30 to 50 years of age and women are affected more than men.
Case Report: We report a case of a 40-year-old man, a worker in a cement factory, who noticed the first skin lesions six years ago. Read More