Schizophr Res 2016 07 28;174(1-3):17-23. Epub 2016 Apr 28.
Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 17177 Stockholm, Sweden. Electronic address:
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Chronobiol Int 2012 Dec 6;29(10):1300-11. Epub 2012 Nov 6.
Department of Medical Sciences, Division of Internal Medicine and Chronobiology Unit , IRCCS Scientific Institute and Regional General Hospital Casa Sollievo della Sofferenza, S. Giovanni Rotondo (FG) , Italy.
The rhythmic recurrence of biological processes is driven by the functioning of cellular circadian clocks, operated by a set of genes and proteins that generate self-sustaining transcriptional-translational feedback loops with a free-running period of about 24 h. In the gastrointestinal apparatus, the functioning of the biological clocks shows distinct patterns in the different organs. The aim of this study was to evaluate the time-related variation of clock gene expression in mouse liver and stomach, two components of the digestive system sharing vascular and autonomic supply, but performing completely different functions. Read More
Arch Oral Biol 2017 Jul 14;79:95-99. Epub 2017 Mar 14.
Department of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria; Austrian Cluster for Tissue Regeneration, Vienna, Austria. Electronic address:
Objective: The circadian clock is involved in a plethora of physiological processes including bone formation and tooth development. While expression of circadian core clock genes was observed in various tissues, their role in the periodontium is unclear. We hypothesized that periodontal cells express circadian core clock genes and that their levels are modulated by hypoxia mimetic agents and hypoxia. Read More
J Biol Rhythms 2016 Feb 2;31(1):68-81. Epub 2015 Nov 2.
Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
The identification and investigation of novel clock-controlled genes (CCGs) has been conducted thus far mainly in model organisms such as nocturnal rodents, with limited information in humans. Here, we aimed to characterize daily and circadian expression rhythms of CCGs in human peripheral blood during a sleep/sleep deprivation (S/SD) study and a constant routine (CR) study. Blood expression levels of 9 candidate CCGs (SREBF1, TRIB1, USF1, THRA1, SIRT1, STAT3, CAPRIN1, MKNK2, and ROCK2), were measured across 48 h in 12 participants in the S/SD study and across 33 h in 12 participants in the CR study. Read More
Vet Immunol Immunopathol 2010 Dec 10;138(3):183-92. Epub 2010 Aug 10.
Department of Animal and Food Sciences, University of Delaware, Newark, DE 19716, USA.
Circadian rhythms are driven by oscillating expression of a family of transcription factors called clock genes. In rodents, clock genes drive circadian rhythms in white blood cell function, and glucocorticoids are believed to regulate these rhythms. Little is known about circadian rhythms of cattle white blood cells. Read More