Pediatr Dermatol 2016 May 13;33(3):e224-5. Epub 2016 Apr 13.
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
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Pediatr Dermatol 2009 Jan-Feb;26(1):87-9
Department of Dermatology, University of Wisconsin, Madison, Wisconsin 53715, USA.
Focal epithelial hyperplasia, or Heck's disease, is an uncommon proliferation of oral mucosa that presents primarily in Native Central and South American populations. It presents as asymptomatic papules or nodules on the oral mucosa, gingiva, tongue, and lips. In the majority of cases, human papilloma virus 13 or 32 is detected. Read More
Arch Iran Med 2010 Jan;13(1):48-52
Kerman Oral and Dental Disease Research Center, Department of Oral Medicine, Kerman University of Medical Sciences, Shafa Street, Kerman, Iran.
Heck's disease or focal epithelial hyperplasia is a benign contagious disease caused by human papillomavirus types 13 or 32. It occurs with low frequency in the Iranian population. This condition is characterized by the occurrence of multiple, small papules or nodules in the oral cavity, especially on the labial and buccal mucosa and tongue. Read More
Pediatr Dent 2011 Nov-Dec;33(7):522-4
Department of Oral Pathology, Gazi University, Ankara, Turkey.
Focal epithelial hyperplasia (FEH), or Heck's disease, is a benign proliferative viral infection of the oral mucosa that is related to Human Papil-lomavirus (HPV), mainly subtypes 13 and 32. Although this condition is known to exist in numerous populations and ethnic groups, the reported cases among Caucasians are relatively rare. It presents as asymptomatic papules or nodules on the oral mucosa, gingiva, tongue, and lips. Read More
Int J Oral Maxillofac Surg 2012 Aug 10;41(8):1001-4. Epub 2011 Dec 10.
State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, China.
Focal epithelial hyperplasia, or Heck's disease, is a relatively rare virus-induced benign disease. To the best of the authors' knowledge it has not been reported in an ethnic Chinese population. The authors report two cases of focal epithelial hyperplasia (FEH) in Chinese patients, which were clinically and histologically in accord with FEH. Read More