Iron bioavailability from fresh cheese fortified with iron-enriched yeast.

Eur J Nutr 2017 Jun 30;56(4):1551-1560. Epub 2016 Mar 30.

Nestlé Research Center, PO Box 44, 1000, Lausanne 26, Switzerland.

Purpose: An iron-enriched yeast able to lyse at body temperature was developed for iron fortification of chilled dairy products. The aim was to evaluate iron (Fe) absorption from iron-enriched yeast or ferrous sulfate added to fresh cheese.

Methods: Two stable isotope studies with a crossover design were conducted in 32 young women. Fe absorption from fresh cheese fortified with iron-enriched yeast (2.5 mg Fe) was compared to that from ferrous sulfate (2.5 mg Fe) when ingested with fresh cheese alone or with fresh cheese consumed with bread and butter. Iron absorption was determined based on erythrocyte incorporation of isotopic labels 14 days after consumption of the last test meal.

Results: Geometric mean fractional iron absorption from fresh cheese fortified with iron-enriched yeast consumed alone was significantly lower than from the cheese fortified with FeSO (20.5 vs. 28.7 %; p = 0.0007). When the fresh cheese was consumed with bread and butter, iron absorption from both fortificants decreased to 6.9 % from the iron-enriched yeast compared to 8.4 % from ferrous sulfate. The relative bioavailability of the iron-enriched yeast compared to ferrous sulfate was 0.72 for the cheese consumed alone and 0.82 for cheese consumed with bread and butter (p = 0.157).

Conclusions: Iron from iron-enriched yeast was 72-82 % as well absorbed as ferrous sulfate indicating that the yeast lysed during digestion and released its iron.

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http://dx.doi.org/10.1007/s00394-016-1200-6DOI Listing
June 2017
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References

(Supplied by CrossRef)

E DeMaeyer et al.
World Health Stat Q 1985

E McLean et al.
Public Health Nutr 2009

S Grantham-McGregor et al.
J Nutr 2001

JD Haas et al.
J Nutr 2001

R Stoltzfus et al.
J Nutr 2001

WHO et al.
2002

WHO & FAO et al.
2006

S Sazawal et al.
BMC Public Health 2013

K Eichler et al.
BMC Public Health 2012

I Mauleñn et al.
Salud Publica Mex 1999

CG Neumann et al.
J Nutr 2003

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