Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms.

Authors:
Takashi Nomura
Takashi Nomura
Yao Municipal Hospital
Japan
Mayumi Katoh
Mayumi Katoh
Graduate School of Medicine
Japan
Yosuke Yamamoto
Yosuke Yamamoto
Kyoto University
Japan
Yoshiki Miyachi
Yoshiki Miyachi
Kyoto University Graduate School of Medicine
Japan
Kenji Kabashima
Kenji Kabashima
Kyoto University Graduate School of Medicine
Japan

J Dermatol 2016 Nov 30;43(11):1301-1306. Epub 2016 Mar 30.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Eosinophilic pustular folliculitis (EPF) is a sterile inflammatory dermatosis of unknown etiology. In addition to classic EPF, which affects otherwise healthy individuals, an immunocompromised state can cause immunosuppression-associated EPF (IS-EPF), which may be referred to dermatologists in inpatient services for assessments. Infancy-associated EPF (I-EPF) is the least characterized subtype, being observed mainly in non-Japanese infants. Diagnosis of EPF is challenging because its lesions mimic those of other common diseases, such as acne and dermatomycosis. Furthermore, there is no consensus regarding the treatment for each subtype of EPF. Here, we created procedure algorithms that facilitate the diagnosis and selection of therapeutic options on the basis of published work available in the public domain. Our diagnostic algorithm comprised a simple flowchart to direct physicians toward proper diagnosis. Recommended regimens were summarized in an easy-to-comprehend therapeutic algorithm for each subtype of EPF. These algorithms would facilitate the diagnostic and therapeutic procedure of EPF.

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Source
http://dx.doi.org/10.1111/1346-8138.13359DOI Listing
November 2016
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