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    [Evaluation of a Post-analysis Method for Cumulative Dose Distribution in Stereotactic Body Radiotherapy].
    Nihon Hoshasen Gijutsu Gakkai Zasshi 2016 Mar;72(3):251-60
    Department of Radiology, University of Tokyo Hospital.
    Purpose: The purpose of this study was to evaluate a post-analysis method for cumulative dose distribution in stereotactic body radiotherapy (SBRT) using volumetric modulated arc therapy (VMAT) .

    Method: VMAT is capable of acquiring respiratory signals derived from projection images and machine parameters based on machine logs during VMAT delivery. Dose distributions were reconstructed from the respiratory signals and machine parameters in the condition where respiratory signals were without division, divided into 4 and 10 phases. The dose distribution of each respiratory phase was calculated on the planned four-dimensional CT (4DCT). Summation of the dose distributions was carried out using deformable image registration (DIR), and cumulative dose distributions were compared with those of the corresponding plans.

    Results And Discussion: Without division, dose differences between cumulative distribution and plan were not significant. In the condition where respiratory signals were divided, dose differences were observed over dose in cranial region and under dose in caudal region of planning target volume (PTV). Differences between 4 and 10 phases were not significant.

    Conclusion: The present method was feasible for evaluating cumulative dose distribution in VMAT-SBRT using 4DCT and DIR.

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