Vet Pathol 2016 07 1;53(4):823-32. Epub 2016 Mar 1.
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, Davis, CA, USA.
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J Feline Med Surg 2010 Dec 30;12(12):929-35. Epub 2010 Oct 30.
Department of Veterinary Pathology, Freie Universität Berlin, Robert-von-Ostertag-Str 15, 14163 Berlin, Germany.
A significant drop in the prevalence of feline leukaemia virus (FeLV) antigenaemic cats and antigen-associated lymphomas has been observed after the introduction of FeLV vaccination and antigen-testing with removal of persistently antigenaemic cats. However, recent reports have indicated that regressively infected cats may contain FeLV provirus DNA and that lymphoma development may be associated with the presence of provirus alone. In the present study, we investigated the presence of FeLV antigen and provirus DNA in 50 lymphomas by immunohistochemistry and semi-nested polymerase chain reaction, respectively. Read More
Vet Pathol 2015 Mar 5;52(2):250-9. Epub 2014 Jun 5.
DIVET, Facoltà di Medicina Veterinaria, Università degli Studi di Milano, Milano, Italy.
Lymphoma is the most common feline upper respiratory tract (URT) tumor. Primary nasal and nasopharyngeal lymphomas have been evaluated as distinct pathological entities; however, data on their differing clinical behavior are missing. A total of 164 endoscopic- guided URT pinch biopsies were formalin fixed and routinely processed. Read More
Ophthalmology 1999 Nov;106(11):2109-20
Department of Pathology, University Hospital Benjamin Franklin, Berlin, Germany.
Objective: Lymphomas of the eye and its adnexa are frequently of B lineage. This study aims to characterize the clinical and histopathologic features of the rare non-B-cell non-Hodgkin lymphomas (NHL) of these locations.
Design: Retrospective, noncomparative case series. Read More
Can J Vet Res 1996 Jul;60(3):199-204
Department of Veterinary Pathology, Western College of Veterinary Medicine, Saskatoon, Saskatchewan.
The lymphocyte phenotype of 70 formalin-fixed, paraffin-embedded feline lymphosarcomas (LSAs) was determined immunohistochemically using a T cell polyclonal antibody, and a B cell monoclonal antibody. Forty-seven of 70 (67%) tumors were T cell, 19/70 (27%) were B cell, and 4/70 (6%) did not stain with either marker. Thirty-eight of 70 (54%) tumors were positive for feline leukemia virus (FeLV) antigen by immunohistochemistry (IHC), and 52/70 (74%) tumors were positive for FeLV DNA using the polymerase chain reaction (PCR). Read More