Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency.

Authors:
Lidia Zueva
Lidia Zueva
Institute for Evolutionary Physiology and Biochemistry
Russia
Tatiana Golubeva
Tatiana Golubeva
Lomonosov State University
Elena Korneeva
Elena Korneeva
School of Life Science
Dr. Vladimir Makarov, PhD
Dr. Vladimir Makarov, PhD
University of Puerto Rico
San Juan, Puerto Rico | United States
Dr. Igor Khmelinskii, PhD, Prof. Agregado
Dr. Igor Khmelinskii, PhD, Prof. Agregado
University of the Algarve
PhD, Prof. Agregado
physcal chemistry; spectroscopy; climate science
Faro, Algarve | Portugal
Dr. Mikhail Inyushin, PhD
Dr. Mikhail Inyushin, PhD
School of Medicine
Assistant Professor
Physiology
Bayamon, Puerto Rico | United States

Microsc Microanal 2016 Apr 1;22(2):379-86. Epub 2016 Mar 1.

6Department of Physiology,Central University of the Caribbean,Bayamon, PR 00956,USA.

Specialized intermediate filaments (IFs) have critical importance for the clearness and uncommon transparency of vertebrate lens fiber cells, although the physical mechanisms involved are poorly understood. Recently, an unusual low-scattering light transport was also described in retinal Müller cells. Exploring the function of IFs in Müller cells, we have studied the morphology and distribution pattern of IFs and other cytoskeletal filaments inside the Müller cell main processes in the foveolar part of the avian (pied flycatcher) retina. We found that some IFs surrounded by globular nanoparticles (that we suggest are crystallines) are present in almost every part of the Müller cells that span the retina, including the microvilli. Unlike IFs implicated in the mechanical architecture of the cell, these IFs are not connected to any specific cellular membranes. Instead, they are organized into bundles, passing inside the cell from the endfeet to the photoreceptor, following the geometry of the processes, and repeatedly circumventing numerous obstacles. We believe that the presently reported data effectively confirm that the model of nanooptical channels built of the IFs may provide a viable explanation of Müller cell transparency.

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http://dx.doi.org/10.1017/S1431927616000507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940978PMC
April 2016
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