Search our Database of Scientific Publications and Authors

I’m looking for a
    Hydroa Vacciniforme-Like EBV-Positive Cutaneous T-Cell Lymphoma, First Report of 2 Cases in Ecuador.
    Am J Dermatopathol 2016 May;38(5):e57-9
    Servicio de Patología, Hospital Metropolitano, Quito, Ecuador.
    Hydroa vacciniforme-like cutaneous lymphoma is a very rare Epstein-Barr virus positive peripheral T-cell lymphoma affecting Asian and Hispanic children and young adults with a defective cytotoxic immune response to EBV predisposing to the development of the disease. We report on 2 Ecuadorian patients with papulovesicular and ulcerated crusted lesions on the face, upper and lower extremities and abdomen, with aggressive clinical course and, in one case, a fatal outcome. The histological and molecular profiles (immunohistochemistry and in situ hybridization) established a diagnosis of hydroa vacciniforme-like Epstein-Barr virus-encoded small RNAs + cutaneous T-cell lymphoma in both cases.

    Similar Publications

    Hydroa vacciniforme-like lymphoma with primarily periorbital swelling: 7 cases of an atypical clinical manifestation of this rare cutaneous T-cell lymphoma.
    Am J Dermatopathol 2015 Jan;37(1):20-5
    *Department of Pathology, Division of Dermatopathology, Medical College of Wisconsin, Milwaukee, WI; and †Department of Pathology and Dermatology, Division of Dermatopathology, Hospital Obrero, La Paz, Bolivia.
    Hydroa vacciniforme-like lymphoma (HVL) is a rare cutaneous T-cell lymphoma that is usually seen in children of Hispanic or Asian origin. Association between chronic latent Epstein-Barr virus infection in both hydroa vacciniforme (HV) and HVL has been demonstrated and has recently been categorized by the World Health Organization as one of the Epstein Barr virus-positive lymphoproliferative disorders of childhood. Patients with HVL present with a cutaneous rash characterized by edema, blisters, ulcers, and scars mainly seen on the face and extremities that mimic HV; however, unlike in HV, the lesions tend to be extensive and deeper and are associated with severe scarring, necrosis, and systemic manifestations. Read More
    Epstein-Barr virus-associated hydroa vacciniforme-like cutaneous lymphoma in seven Chinese children.
    Pediatr Dermatol 2010 Sep-Oct;27(5):463-9
    Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
    Hydroa vacciniforme-like cutaneous lymphoma is a rare type of Epstein-Barr virus-associated lymphoma. We analyze clinicopathologic features of seven Chinese child patients with hydroa vacciniforme-like cutaneous lymphoma and determine the pathogenic association of Epstein-Barr virus with this disorder. Clinical, histologic, and immunohistochemical features were reviewed. Read More
    EBV-associated cutaneous NK/T-cell lymphoma: review of a series of 14 cases from peru in children and young adults.
    Am J Surg Pathol 2010 Dec;34(12):1773-82
    Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre, CNIO, Madrid, Spain.
    We have reviewed clinically, morphologically, and immunophenotypically a series of 14 Epstein-Bar virus (EBV)+ cutaneous natural killer cell (NK)/T-cell lymphoma from Peru. Most (11 out of 14) of these cases fit well into the category of Hydroa vacciniforme-like lymphoma (HVLL), but 3 have a different clinical presentation, without facial involvement. In all 14 cases, skin lesions present in both the sun-exposed and nonexposed areas exhibited a slowly progressive relapsing course, changing from edema, to blistering, ulceration, and final scarring. Read More