Am J Dermatopathol 2016 May;38(5):e57-9
Servicio de Patología, Hospital Metropolitano, Quito, Ecuador.
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Am J Dermatopathol 2015 Jan;37(1):20-5
*Department of Pathology, Division of Dermatopathology, Medical College of Wisconsin, Milwaukee, WI; and †Department of Pathology and Dermatology, Division of Dermatopathology, Hospital Obrero, La Paz, Bolivia.
Hydroa vacciniforme-like lymphoma (HVL) is a rare cutaneous T-cell lymphoma that is usually seen in children of Hispanic or Asian origin. Association between chronic latent Epstein-Barr virus infection in both hydroa vacciniforme (HV) and HVL has been demonstrated and has recently been categorized by the World Health Organization as one of the Epstein Barr virus-positive lymphoproliferative disorders of childhood. Patients with HVL present with a cutaneous rash characterized by edema, blisters, ulcers, and scars mainly seen on the face and extremities that mimic HV; however, unlike in HV, the lesions tend to be extensive and deeper and are associated with severe scarring, necrosis, and systemic manifestations. Read More
Pediatr Dermatol 2010 Sep-Oct;27(5):463-9
Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Hydroa vacciniforme-like cutaneous lymphoma is a rare type of Epstein-Barr virus-associated lymphoma. We analyze clinicopathologic features of seven Chinese child patients with hydroa vacciniforme-like cutaneous lymphoma and determine the pathogenic association of Epstein-Barr virus with this disorder. Clinical, histologic, and immunohistochemical features were reviewed. Read More
J Cutan Pathol 2015 Mar 8;42(3):229-31. Epub 2014 Dec 8.
Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Am J Surg Pathol 2010 Dec;34(12):1773-82
Lymphoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre, CNIO, Madrid, Spain.
We have reviewed clinically, morphologically, and immunophenotypically a series of 14 Epstein-Bar virus (EBV)+ cutaneous natural killer cell (NK)/T-cell lymphoma from Peru. Most (11 out of 14) of these cases fit well into the category of Hydroa vacciniforme-like lymphoma (HVLL), but 3 have a different clinical presentation, without facial involvement. In all 14 cases, skin lesions present in both the sun-exposed and nonexposed areas exhibited a slowly progressive relapsing course, changing from edema, to blistering, ulceration, and final scarring. Read More