Diagnostics (Basel) 2012 Mar 20;2(1). Epub 2012 Mar 20.
Guest Editor, Biomedical Diagnostics Institute, National Centre of Sensor Research, School of Physical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.
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J Multidiscip Healthc 2018 28;11:405-416. Epub 2018 Aug 28.
School of Public Health, The Joanna Briggs Institute, The University of Adelaide, Adelaide, SA, Australia,
Introduction: Policy makers and health professionals prefer to use preappraised and summarized evidence. Stigma and discrimination (SAD) reduction activities and programs are needed to improve the quality of care delivered to people living with HIV and the success of HIV-related prevention, care and treatment programs. The objective of this review was to identify and describe systematic reviews, best practices, consensus statements, standards of practice and guidelines that addressed SAD among healthcare workers (HCWs). Read More
Pediatrics 2018 Sep 20;142(3). Epub 2018 Aug 20.
Preventive Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Systemic hypertension is a major cause of morbidity and mortality in adulthood. High blood pressure (HBP) and repeated measures of HBP, hypertension (HTN), begin in youth. Knowledge of how best to diagnose, manage, and treat systemic HTN in children and adolescents is important for primary and subspecialty care providers. Read More
PLoS One 2018 23;13(5):e0192425. Epub 2018 May 23.
Department of Rheumatology, VieCuri Medical Center, Venlo, The Netherlands.
Objective: Successfully stopping or reducing treatment for patients with rheumatoid arthritis (RA) in low disease activity (LDA) may improve cost-effectiveness of care. We evaluated the multi-biomarker disease activity (MBDA) score as a predictor of disease relapse after discontinuation of TNF inhibitor (TNFi) treatment.
Methods: 439 RA patients who were randomized to stop TNFi treatment in the POET study were analyzed post-hoc. Read More
Ci Ji Yi Xue Za Zhi 2017 Apr-Jun;29(2):98-103
Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Objective: Pregnant women infected with malaria represent a significant obstetric problem, especially in the face of antimalarial resistance. This cross-sectional study investigated the prevalence of malaria parasitemia, associated risk factors as well as the antimalarial resistance pattern of isolates from pregnant women attending four selected secondary health facilities in Kaduna State, Nigeria.
Materials And Methods: Blood samples were collected from 353 pregnant women attending selected hospitals. Read More
BMC Genomics 2017 03 13;18(1):227. Epub 2017 Mar 13.
Centro Regional de Estudio Génomicos, Universidad Nacional de La Plata, Boulevard 120, La Plata, Argentina.
Background: For a long time synonymous single nucleotide polymorphisms were considered as silent mutations. However, nowadays it is well known that they can affect protein conformation and function, leading to altered disease susceptibilities, differential prognosis and/or drug responses, among other clinically relevant genetic traits. This occurs through different mechanisms: by disrupting the splicing signals of precursor mRNAs, affecting regulatory binding-sites of transcription factors and miRNAs, or by modifying the secondary structure of mRNAs. Read More