Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.

Cell Metab 2016 Jan;23(1):10-2

Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden; Lundberg Laboratory for Diabetes Research, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

Type 2 diabetes (T2D) is associated with dysbiosis of the gut microbiota, though diabetes treatment regimens, including metformin, may confound the results. Forslund et al. (2015) identify distinct disease and drug signatures and highlight the importance of adjusting for treatment when investigating how T2D influences the human gut microbiome.

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http://www.cell.com/cell-metabolism/pdf/S1550-4131(15)00627-
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http://linkinghub.elsevier.com/retrieve/pii/S155041311500627
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http://dx.doi.org/10.1016/j.cmet.2015.12.012DOI Listing
January 2016
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