JAMA Neurol 2016 Mar;73(3):355-6
Department of Dermatology, University of Pennsylvania, Philadelphia.
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Intern Med 2016;55(22):3383-3386. Epub 2016 Nov 15.
Department of General Internal Medicine, Kobe University Hospital, Japan.
We herein report the case of a 63-year-old man who presented with a 3-month history of a cutaneous nodular lesion of his jaw, low grade fever, lethargy and progressive cognitive impairment. He had a 30-year history of multiple sclerosis and had been treated with fingolimod for the previous 2 years. Laboratory data revealed CD4 lymphocytopenia and a tissue culture of the skin nodule was positive for Cryptococcus neoformans. Read More
Mult Scler 2017 Feb;23(2):297-299
St Croix Dermatology, Stillwater, MN, USA.
Background: Fingolimod is an oral disease-modifying therapy for relapsing forms of multiple sclerosis, which acts by sequestering lymphocytes within lymph nodes.
Objective: To describe a case of extrapulmonary cryptococcosis in a patient taking fingolimod.
Methods: Case report. Read More
Mult Scler 2015 May 28;21(6):795-6. Epub 2014 Nov 28.
Department of Neurology, NIMTS Hospital, Athens, Greece.
Neurology 2015 Sep 19;85(11):1001-3. Epub 2015 Aug 19.
From the Multiple Sclerosis Center, Neurology and Neuroscience Associates, Unity Health Network, Akron, OH.