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    Primary Cutaneous Cryptococcus in a Patient With Multiple Sclerosis Treated With Fingolimod.
    JAMA Neurol 2016 Mar;73(3):355-6
    Department of Dermatology, University of Pennsylvania, Philadelphia.

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    Disseminated Cryptococcosis in a 63-year-old Patient with Multiple Sclerosis Treated with Fingolimod.
    Intern Med 2016;55(22):3383-3386. Epub 2016 Nov 15.
    Department of General Internal Medicine, Kobe University Hospital, Japan.
    We herein report the case of a 63-year-old man who presented with a 3-month history of a cutaneous nodular lesion of his jaw, low grade fever, lethargy and progressive cognitive impairment. He had a 30-year history of multiple sclerosis and had been treated with fingolimod for the previous 2 years. Laboratory data revealed CD4 lymphocytopenia and a tissue culture of the skin nodule was positive for Cryptococcus neoformans. Read More