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Ann Surg 2022 Jun 28. Epub 2022 Jun 28.

Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.

Objective: To determine cell-specific gene expression profiles that contribute to development of abdominal aortic aneurysms (AAAs).

Background: AAAs represent the most common pathological aortic dilation leading to the fatal consequence of aortic rupture. Both immune and structural cells contribute to aortic degeneration, however, gene specific alterations in these cellular subsets are poorly understood. Read More

J Biol Chem 2022 Jun 24:102196. Epub 2022 Jun 24.

Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois 62901. Electronic address:

In human cells, ATP is generated using oxidative phosphorylation machinery, which is inoperable without proteins encoded by mitochondrial DNA (mtDNA). The DNA polymerase gamma (Polγ) repairs and replicates the multicopy mtDNA genome in concert with additional factors. The Polγ catalytic subunit is encoded by the POLG gene, and mutations in this gene cause mtDNA genome instability and disease. Read More

Genome Biol Evol 2022 Jun 27. Epub 2022 Jun 27.

UMR7141, Institut de Biologie Physico-Chimique (CNRS/Sorbonne Université), 13 Rue Pierre et Marie Curie, 75005 Paris, France.

Most of the proteins present in mitochondria and chloroplasts, the organelles acquired via endosymbiotic events, are encoded in the nucleus and translated into the cytosol. Most of such nuclear-encoded proteins are specifically recognized via an N-terminal encoded Targeting Peptide (TP) and imported into the organelles via a translocon machinery. Once imported, the TP is degraded by a succession of cleavage steps ensured by dedicated peptidases. Read More

Mitochondrial DNA B Resour 2022 14;7(6):1030-1031. Epub 2022 Jun 14.

Pharmacy College, Heilongjiang University of Chinese Medicine, Harbin, China.

refers to a perennial herb with both ornamental and medicinal value. In the present study, we obtained the complete chloroplast genome sequence of through high-throughput sequencing. The length of the chloroplast genome was 157,139 bp, while the large single-copy and small single-copy regions were 84,478 bp and 18,587 bp, respectively. Read More

Mitochondrial DNA B Resour 2022 15;7(6):1027-1029. Epub 2022 Jun 15.

Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.

The Pacific seabream, , is a commercially valuable resource for fisheries around the West Pacific Ocean countries. Although the phylogenetic position of the within the genus changes by the differences in the target gene regions or fish sampling locations, the genetic information of the species is quite limited. In this study, the complete mitochondrial genome of from Iriomotejima Island, Okinawa, Japan was determined. Read More