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Role of DFNA5 in hearing loss and cancer - a comment on Rakusic et al.

Authors:
Lieselot Croes Ken Op de Beeck Guy Van Camp

Onco Targets Ther 2015 15;8:2613-5. Epub 2015 Sep 15.

Center of Medical Genetics (CMG), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.2147/OTT.S91168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592022PMC
October 2015

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Liver transplantation is considered the most curative treatment for patients with localized hepatocellular carcinoma (HCC). Recent organ allocation policies have reduced the priority of patients with HCC for liver transplantation, which might affect overall liver transplantation usage and HCC-specific mortality among patients with HCC. Therefore, studies on the impact of liver transplantation on population-level HCC-specific mortality rates are necessary and essential. Read More

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Division of Cancer Prevention, NCI, Rockville, Maryland.

Intraductal assessment of the breast holds the potential to provide useful information regarding breast cancer risk assessment, early diagnosis, and/or response to therapy. Intraductal assessment can be through imaging (ductography), direct visualization (mammary ductoscopy), or evaluation of the intraductal fluid collected. The most common nonradiologic approaches to intraductal assessment that provide intraductal fluid for evaluation include breast nipple aspiration fluid (NAF), spontaneous nipple discharge (SND), mammary ductoscopy, and ductal lavage. Read More

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Reducing Racial Disparities in Surviving Gastrointestinal Cancer Will Require Looking Beyond the Fact That African-Americans Have Low Rates of Surgery.

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Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.

This article by Bliton and colleagues in this issue of the journal concludes that disproportionately low surgery rates among Black patients contribute to the known survival disparity between Blacks and Whites. Using data from the National Cancer Database (NCDB), they were able to address the implicit hypothesis that the measured outcome disparities are partly attributable to failure to deliver surgical care equitably. As with most good research on difficult and complex topics, it also raises interesting and provocative questions about the role of race in poor survival among African-American patients with gastrointestinal cancer. Read More

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