Clin Chem Lab Med 2016 Mar;54(3):493-9
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J Clin Microbiol 2016 Apr 10;54(4):1101-7. Epub 2016 Feb 10.
Prof. Gisela Enders & Kollegen MVZ GbR, Stuttgart, Germany.
Quantitating the level of hepatitis C virus (HCV) RNA is the standard of care for monitoring HCV-infected patients during treatment. The performances of commercially available assays differ for precision, limit of detection, and limit of quantitation (LOQ). Here, we compare the performance of the Hologic Aptima HCV Quant Dx assay (Aptima) to that of the Roche Cobas TaqMan HCV test, version 2. Read More
J Clin Virol 2017 07 8;92:14-19. Epub 2017 May 8.
Department of Clinical Microbiology 445, Hvidovre Hospital, Kettegård Alle 30, DK-2650 Hvidovre, Denmark; Department for Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Background: HIV-RNA is the most important parameter for monitoring antiviral treatment in individuals infected with HIV-1. Knowledge of the performance of different tests for the quantification of HIV-1 RNA is therefore important for clinical care.
Objectives: To compare the analytical performance of the Aptima HIV-1 Quant Dx Assay (Aptima) and the COBAS Ampliprep/COBAS TaqMan HIV-1 Test v2. Read More
J Clin Virol 2015 Aug 29;69:56-62. Epub 2015 May 29.
University of Liverpool, Liverpool, United Kingdom.
Background: Quantitative measurement of HIV-1 RNA levels in plasma ('viral load') plays a central role in clinical management. The choice of assay platform can influence results and treatment decisions.
Objective: To compare the analytical performance of the new TMA-based Hologic Aptima(®) HIV-1 Quant Dx assay with that of three PCR-based assays: Abbott RealTime HIV-1, Qiagen Artus(®) HI Virus-1 QS-RGQ, and Roche CAP/CTM HIV-1 Test v2. Read More
Virol J 2017 04 4;14(1):66. Epub 2017 Apr 4.
Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, GR-11527, Athens, Greece.
Background: The Aptima HCV Quant Dx assay (Aptima assay) is a fully automated quantitative assay on the Panther® system. This assay is intended for confirmation of diagnosis and monitoring of HCV RNA in plasma and serum specimens. The purpose of the testing described in this paper was to evaluate the performance of the Aptima assay. Read More