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Plant Physiol Biochem 2021 Feb 22;162:124-136. Epub 2021 Feb 22.

Key Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin, 150040, China; College of Life Science, Northeast Forestry University, Harbin, 150040, China. Electronic address:

The purple pigmentation in the epidermis of swollen roots of 'Tsuda' turnip (Brassica rapa subsp. rapa) is induced by light, providing a good system to investigate the genetic mechanism of light-dependent anthocyanin biosynthesis in B. rapa. Read More

Phytomedicine 2021 Feb 14;85:153514. Epub 2021 Feb 14.

School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin, 301617, China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address:

Background: Prostate cancer (PCa) is a major cause of morbidity and mortality in men in both developed and developing countries. Androgens and the androgen receptor (AR) play predominant roles in the progression of PCa. Neoisoliquiritin (NEO) belongs to the class of licorice (Glycyrrhiza) flavonoids, which have a variety of biological activities including anti-depressant, anti-tumor-promoting, and anti-inflammation properties. Read More

Int J Infect Dis 2021 Mar 3. Epub 2021 Mar 3.

Department of Infectious Diseases, Peking University First Hospital, Beijing, 100034, China. Electronic address:

Objectives: To investigate the factors and the virological significance of serum hepatitis B virus (HBV) pgRNA after long-term antiviral therapy with nucleos(t)ide analogues (NAs) in chronic hepatitis B (CHB) patients.

Methods: In total, 51 treatment-naïve CHB patients were included in the study. Clinical data were collected at baseline and after 5 years and at year 10 of antiviral treatment. Read More

Ann Hepatol 2021 Mar 3:100339. Epub 2021 Mar 3.

Área de Medicina Experimental y Traslacional, Departamento de Ciencias de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico; Laboratorio de Medicina Experimental, Unidad de Medicina Traslacional, IIB, UNAM/Instituto Nacional de Cardiología Ignacio Chavez, Mexico City, Mexico. Electronic address:

Introduction And Objectives: It is well-known that signaling mediated by the hepatocyte growth factor (HGF) and its receptor c-Met in the liver is involved in the control of cellular redox status and oxidative stress, particularly through its ability to induce hepatoprotective gene expression by activating survival pathways in hepatocytes. It has been reported that HGF can regulate the expression of some members of the NADPH oxidase family in liver cells, particularly the catalytic subunits and p22. In the present work we were focused to characterize the mechanism of regulation of p22 by HGF and its receptor c-Met in primary mouse hepatocytes as a key determinant for cellular redox regulation. Read More

J Ethnopharmacol 2021 Mar 3:113986. Epub 2021 Mar 3.

College of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil; Gonçalo Moniz Institute, FIOCRUZ, Salvador, Bahia, Brazil. Electronic address:

Ethnopharmacological Relevance: Physalis angulata is an herb found in tropical and subtropical regions of the world; it is widely applied in popular medicine due to the therapeutic properties of the whole plant and its parts. Extracts and infusions of this plant have been extensively applied in folk medicine worldwide to treat inflammatory and immune-mediated diseases, including oral inflammatory conditions such as sore throat and gingivitis.

Aim Of The Study: The present study was designed to investigate the protective effects of the ethanolic extract of P. Read More