Circ Cardiovasc Imaging 2016 Jun;9(6)
From the Department of Internal Medicine and Medical Specialties (C.L.), and Department of Cardiovascular, Respiratory, Nephrology, Anesthetic, and Geriatric Sciences (S.S.), University La Sapienza, Rome, Italy; Unit of Internal Medicine and Hepatology, Department of Medicine, University of Padova, Italy (P.A., S.R.); and Hypertension Clinic, Department of Medicine-DIMED, University of Padova, Italy (M.C., G.P.R.).
Background: Primary aldosteronism (PA) causes excess left ventricular (LV) hypertrophy and diastolic dysfunction; whether this occurs also in secondary aldosteronism (SA) without hypertension is unknown. We investigated the cardiac modifications in patients with preserved LV ejection fraction who had PA or SA.
Methods And Results: We measured several Doppler echocardiography-derived variables, including tissue Doppler imaging (TDI) parameters and strain rate analysis, in 262 patients with PA, 117 with SA because of liver cirrhosis, and in 61 control healthy subjects. Read More