Epidemiol Infect 2016 Feb 23;144(3):478-92. Epub 2015 Jul 23.
Institute of Industrial Science,the University of Tokyo,Komaba,Meguro,Tokyo,Japan.
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PLoS One 2013 8;8(7):e67934. Epub 2013 Jul 8.
Onoda Hospital, Minamisoma City, Fukushima, Japan.
Background: Kawasaki disease (KD) is a common cause of acquired paediatric heart disease in developed countries. KD was first identified in the 1960s in Japan, and has been steadily increasing since it was first reported. The aetiology of KD has not been defined, but is assumed to be infection-related. Read More
Pediatr Infect Dis J 2005 Nov;24(11):1011-4
Department of Pediatrics, University of California-San Diego School of Medicine, San Diego, CA, USA.
Clinical similarities and shared seasonality suggested a relationship between adenovirus infection and Kawasaki disease. We performed adenovirus serology and quantitative polymerase chain reaction for both adenovirus and adeno-associated virus in patients with acute Kawasaki disease. No evidence was found to suggest a link between either virus and Kawasaki disease. Read More
Pediatrics 2000 Aug;106(2):E27
Department of Pediatrics, University of California San Diego, La Jolla, California 92093-0830, USA.
Tomisaku Kawasaki published the first English-language report of 50 patients with Kawasaki disease (KD) in 1974. Since that time, KD has become the leading cause of acquired heart disease among children in North America and Japan. Although an infectious agent is suspected, the cause remains unknown. Read More
Int J Infect Dis 2005 Jul;9(4):185-94
School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital for Children, GPO Box D184, Perth WA 6840, Australia.
Kawasaki disease (KD) is an important and common inflammatory vasculitis of early childhood with a striking predilection for the coronary arteries. It is the predominant cause of paediatric acquired heart disease in developed countries. Despite 40 years of research, the aetiology of KD remains unknown and consequently there is no diagnostic test and treatment is non-specific and sub-optimal. Read More