Cardiac Magnetic Resonance Scar Imaging for Sudden Cardiac Death Risk Stratification in Patients with Non-Ischemic Cardiomyopathy.

Korean J Radiol 2015 Jul-Aug;16(4):683-95. Epub 2015 Jul 1.

Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, NC 27710, USA. ; Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA.

In patients with non-ischemic cardiomyopathy (NICM), risk stratification for sudden cardiac death (SCD) and selection of patients who would benefit from prophylactic implantable cardioverter-defibrillators remains challenging. We aim to discuss the evidence of cardiac magnetic resonance (CMR)-derived myocardial scar for the prediction of adverse cardiovascular outcomes in NICM. From the 15 studies analyzed, with a total of 2747 patients, the average prevalence of myocardial scar was 41%. In patients with myocardial scar, the risk for adverse cardiac events was more than 3-fold higher, and risk for arrhythmic events 5-fold higher, as compared to patients without scar. Based on the available observational, single center studies, CMR scar assessment may be a promising new tool for SCD risk stratification, which merits further investigation.

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http://dx.doi.org/10.3348/kjr.2015.16.4.683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499533PMC
February 2016
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