Synthesis of disulfide-based biodegradable bridged silsesquioxane nanoparticles for two-photon imaging and therapy of cancer cells.

Authors:
Dr. Jonas G Croissant, PhD
Dr. Jonas G Croissant, PhD
University of New Mexico, Chemical & Biological Engineering
Research Assistant Professor
Chemistry, Materials Science
Albuquerque, New Mexico | United States
Marie Maynadier
Marie Maynadier
NanoMedSyn
Montpellier | France
Laurence Raehm
Laurence Raehm
Institut Charles Gerhardt Montpellier
Montpellier | France
Olivier Mongin
Olivier Mongin
Université de Rennes 1
Rennes | France

Chem Commun (Camb) 2015 Aug;51(61):12324-7

Institut Charles Gerhardt Montpellier, UMR-5253 CNRS-UM-ENSCM cc 1701, Place Eugene Bataillon, F-34095 Montpellier Cedex 05, France.

Biodegradable bridged silsesquioxane (BS) nanomaterials for two-photon-excited (TPE) imaging and therapy of breast cancer cells were described. A versatile synthesis was developed to design monodisperse tetra-alkoxysilylated diamino-diphenylbutadiene or Zn-porphyrin-based nanospheres of 30 to 50 nm.

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August 2015
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