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Is intrauterine surgery justified? Report from the working group on ultrasound in obstetrics of the World Association of Perinatal Medicine (WAPM).

Authors:
Renato Augusto Moreira de Sá Paulo Roberto Nassar de Carvalho Asim Kurjak Abdallah Adra Aliyu Labaran Dayyabu Alaa Ebrashy Ritsuko Pooh Cihat Sen Tuangsit Wataganara Milan Stanojevic

J Perinat Med 2016 Oct;44(7):737-743

Fetal surgery involves a large number of heterogeneous interventions that vary from simple and settled procedures to very sophisticated or still-in-development approaches. The overarching goal of fetal interventions is clear: to improve the health of children by intervening before birth to correct or treat prenatally diagnosed abnormalities. This article provides an overview of fetal interventions, ethical approaches in fetal surgery, and benefits obtained from antenatal surgeries.

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http://dx.doi.org/10.1515/jpm-2015-0132DOI Listing
October 2016

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Application of Tissue Engineering and Regenerative Medicine in Prelabor Rupture of Membranes: a Review of the Current Evidence.

Authors:
Young Mi Jung Chan-Wook Park Joong Shin Park Jong Kwan Jun Seung Mi Lee

Reprod Sci 2021 Apr 13. Epub 2021 Apr 13.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.

Preterm prelabor rupture of membranes (PPROM) is the main cause of preterm delivery, resulting in increased perinatal morbidity and mortality. Several techniques have been studied for the healing of ruptured membranes, with some success. Before new techniques using tissue/organ engineering are applied in clinical practice, these techniques must be validated in clinical trials. Read More

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Risk of preterm birth and neonatal outcomes after cerclage placement in triplet pregnancies.

Authors:
Gustavo Vilchez Komal Kumar Som Singh Neil Patel Monica Kao Moraima Lagos Jose Duncan

J Matern Fetal Neonatal Med 2021 Apr 13:1-7. Epub 2021 Apr 13.

Department of Obstetrics and Gynecology, University of South Florida, Tapa, FL, USA.

Background: The number of triplet pregnancies in the United States has increased significantly. Perinatal morbidity and mortality are higher in these pregnancies mainly due to higher preterm birth rates. Interventions to decrease the risk of preterm delivery in this population are needed. Read More

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A novel technique in the management of severe postpartum uterine atony bleeding: Three vertical uterine compression sutures.

Authors:
Ismail Ozdemir Ozge Ozdemir Zeynep Ozkose

Eur J Obstet Gynecol Reprod Biol 2021 Apr 2;260:208-211. Epub 2021 Apr 2.

Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Unit, Istanbul Kanuni Sultan Suleyman Health Training and Research Medical Center, Hamidiye School of Medicine, University of Health Sciences, Istanbul, Turkey.

Objective: Postpartum hemorrhage is a leading cause of maternal morbidity and mortality worldwide. Uterine atony is the most common cause of bleeding accounting for ∼80 % of cases of postpartum hemorrhage. To reduce maternal morbidity and mortality due to bleeding caused by uterine atony even under limited resources, a simple and effective procedure that can be easily applied by all obstetricians and junior physicians is required. Read More

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Risk of Recurrent Stillbirth: A Cohort Study.

Authors:
Stephen L Wood Selphee Tang

BJOG 2021 Apr 9. Epub 2021 Apr 9.

Department of Obstetrics and Gynecology Foothills Medical Center, Alberta Health Services, Canada.

Objectives: To evaluate the recurrence risk of stillbirth.

Design: Retrospective cohort study.

Setting And Population: All births 1992-2017, Alberta, Canada METHODS: Retrospective cohort study. Read More

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First-Trimester Serum BAFF:sFlt-1 Ratio as a Candidate Early Biomarker of Spontaneous Abortions.

Authors:
Hindi E Stohl Ning Yu William Stohl

Am J Reprod Immunol 2021 Apr 9:e13428. Epub 2021 Apr 9.

Los Angeles County + University of Southern California Medical Center and Keck School of Medicine of the University of Southern California, Division of Rheumatology, Department of Medicine, Los Angeles, CA, USA.

Problem: Immunologic, angiogenic, and anti-angiogenic factors are associated with spontaneous abortion (SAB). B-cell activating factor (BAFF), a proliferation-inducing ligand (APRIL), placental growth factor (PlGF), and soluble fms-like tyrosine kinase-1 (sFlt-1) may play a role in SAB and may serve singly or in combination as an early biomarker of SAB.

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