Antimutagenic and anticancer activity of Al Madinah Alhasawy mint (Mentha longifolia) leaves extract.

Authors:
Prof. Hesham El-Beshbishy, PhD
Prof. Hesham El-Beshbishy, PhD
Prof. Medical Biochemistry and Molecular Biology
Professor
Medical Biochemistry and Molecular Biology
Madina, Madina | SA

Pak J Biol Sci 2014 Dec;17(12):1231-6

Mentha is one of the genera of Lamiaceae family. The aim of the present study was to evaluate the antimutagenic and anticancer activity of the water and methanolic extract of Alhasawy mint (Mentha longifolia), that grown in Madina Province, western region, Saudi Arabia using three different bioassays namely; Brine shrimp bioassay, Ames mutagenicity bioassay using 3 Hist-Salmonella typhimurium strains of different mutations (TA98, TA97 and TA100) and 2 reference mutagenic drugs nitrosopiperidine (NP) and 2-amino-3-methylimidazo-quinolidine (IQ) and Mammalian cell lines bioassays using 2 different cell lines HepG2 and Vero cell lines. The plant extract showed an efficient antimutagenic activity against the studied bioassays in a directly proportional effect with concentration.

Download full-text PDF

Source
http://dx.doi.org/10.3923/pjbs.2014.1231.1236DOI Listing
December 2014
15 Reads

Publication Analysis

Top Keywords

cell lines
12
mint mentha
8
antimutagenic anticancer
8
alhasawy mint
8
mentha longifolia
8
anticancer activity
8
strains mutations
4
hist-salmonella typhimurium
4
typhimurium strains
4
bioassay hist-salmonella
4
reference mutagenic
4
ta100 reference
4
ta97 ta100
4
ta98 ta97
4
mutations ta98
4
bioassay ames
4
arabia three
4
saudi arabia
4
region saudi
4
western region
4

Similar Publications