Clinical effectiveness and safety of a distraction-rotation knee brace for medial knee osteoarthritis.

Ann Phys Rehabil Med 2015 Jun 23;58(3):126-31. Epub 2015 May 23.

Inserm U1093, université de Bourgogne, 21079 Dijon, France; CIC-P Inserm 803, plateforme d'investigation technologique, CHU de Dijon, 21078 Dijon, France.

Objective: Evaluation of the clinical effectiveness and safety of a new custom-made valgus knee brace (OdrA) in medial knee osteoarthritis (OA) in terms of pain and secondary symptoms.

Methods: Open-label prospective study of patients with symptomatic medial knee OA with clinical evaluation at 6 and 52 weeks (W6, W52). We systematically assessed pain on a visual analog scale (VAS), Knee injury and Osteoarthritis Outcome Score (KOOS), spatio-temporal gait variables, use of nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic-sparing effects of the brace and tolerance. Mean scores were compared at baseline, W6 and W52 and the effect size (ES) and 95% confidence intervals (95% CIs) were calculated.

Results: We included 20 patients with knee OA (mean age 64.2±10.2 years, mean body mass index 27.2±5.4 kg/m2). VAS pain and KOOS were improved at W6 and W52: pain (ES=0.9 at 1 year), amelioration of other symptoms (ES=0.4), and function in activities of daily living (ES=1.1), sports and leisure (ES=1.5), quality of life (ES=0.9) and gait speed (ES=0.41). In total, 76% of patients showed clinical improvement at 1 year. Analgesic and NSAIDs consumption was significantly decreased at W6 and W52. One serious adverse effect noted was lower-limb varices, and observance was deemed satisfactory at 1 year.

Conclusion: This new unloader brace appeared to have good effect on medial knee OA, with an acceptable safety profile and good patient compliance.

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Source
https://linkinghub.elsevier.com/retrieve/pii/S18770657150005
Publisher Site
http://dx.doi.org/10.1016/j.rehab.2015.03.004DOI Listing
June 2015
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