Numerous Howell-Jolly bodies in a patient with idiopathic splenic calcification.

Br J Haematol 2015 Jun 28;169(6):767. Epub 2015 Apr 28.

Department of Pathology (Haematology) and Clinical Haematology, Alfred Health, Melbourne, Vic., Australia.

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June 2015

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Potential role of Howell-Jolly bodies in identifying functional hyposplenism: a prospective single-institute study.

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Department of Internal Medicine, Division of Hematology, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute, 480-1195, Japan.

Although patients with cancer and immunosuppression are at a risk of functional hyposplenism, how to detect it promptly remains unclear. Since hyposplenism allows erythrocytes with nuclear remnants (Howell-Jolly bodies [HJBs]) to appear in the peripheral blood, HJB detection by a routine microscopic examination may help identify patients with functional hyposplenism. This prospective study was thus performed to determine the underlying diseases in patients who presented with HJBs. Read More

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October 2020