Electrostatic assembly/disassembly of nanoscaled colloidosomes for light-triggered cargo release.

Authors:
Dr. Jonas G Croissant, PhD
Dr. Jonas G Croissant, PhD
University of New Mexico, Chemical & Biological Engineering
Research Assistant Professor
Chemistry, Materials Science
Albuquerque, New Mexico | United States

Angew Chem Int Ed Engl 2015 Jun 27;54(23):6804-8. Epub 2015 Apr 27.

Smart Hybrid Materials (SHMs), Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900 (KSA; Saudi Arabia).

Colloidosome capsules possess the potential for the encapsulation and release of molecular and macromolecular cargos. However, the stabilization of the colloidosome shell usually requires an additional covalent crosslinking which irreversibly seals the capsules, and greatly limits their applications in large-cargos release. Herein we report nanoscaled colloidosomes designed by the electrostatic assembly of organosilica nanoparticles (NPs) with oppositely charged surfaces (rather than covalent bonds), arising from different contents of a bridged nitrophenylene-alkoxysilane [NB; 3-nitro-N-(3-(triethoxysilyl)propyl)-4-(((3-(triethoxysilyl)propyl)-amino)methyl)benzamid] derivative in the silica. The surface charge of the positively charged NPs was reversed by light irradiation because of a photoreaction in the NB moieties, which impacted the electrostatic interactions between NPs and disassembled the colloidosome nanosystems. This design was successfully applied for the encapsulation and light-triggered release of cargos.

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http://dx.doi.org/10.1002/anie.201501615DOI Listing
June 2015
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References

(Supplied by CrossRef)

Dinsmore et al.
Science 2002

Li et al.
Angew. Chem. Int. Ed. 2011

Angew. Chem. 2011

Wang et al.
Angew. Chem. Int. Ed. 2012

Angew. Chem. 2012

Stephenson et al.
Chem. Commun. 2014

Sander et al.
Langmuir 2013

Samanta et al.
Small 2009

Maas et al.
Part. Part. Syst. Charact. 2014

Noble et al.
J. Am. Chem. Soc. 2004

Bollhorst et al.
Angew. Chem. 2015

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