Nat Neurosci 2015 May 30;18(5):773-8. Epub 2015 Mar 30.
1] The Saban Research Institute of Children's Hospital, Los Angeles, California, USA.  Department of Pediatrics of the Keck School of Medicine, University of Southern California, Los Angeles, California, USA.  The Pediatric Imaging, Neurocognition, and Genetics Study, San Diego, California, USA.
Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. We investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1,099 typically developing individuals between 3 and 20 years of age. Income was logarithmically associated with brain surface area. Among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data imply that income relates most strongly to brain structure among the most disadvantaged children.