Family income, parental education and brain structure in children and adolescents.

Nat Neurosci 2015 May 30;18(5):773-8. Epub 2015 Mar 30.

1] The Saban Research Institute of Children's Hospital, Los Angeles, California, USA. [2] Department of Pediatrics of the Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [3] The Pediatric Imaging, Neurocognition, and Genetics Study, San Diego, California, USA.

Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. We investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1,099 typically developing individuals between 3 and 20 years of age. Income was logarithmically associated with brain surface area. Among children from lower income families, small differences in income were associated with relatively large differences in surface area, whereas, among children from higher income families, similar income increments were associated with smaller differences in surface area. These relationships were most prominent in regions supporting language, reading, executive functions and spatial skills; surface area mediated socioeconomic differences in certain neurocognitive abilities. These data imply that income relates most strongly to brain structure among the most disadvantaged children.

Download full-text PDF

Source
http://www.columbia.edu/cu/needlab/Publications/PING%20Natur
Web Search
http://www.nature.com/doifinder/10.1038/nn.3983
Publisher Site
http://dx.doi.org/10.1038/nn.3983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414816PMC
May 2015
68 Reads

Publication Analysis

Top Keywords

surface area
16
brain structure
12
differences surface
8
income families
8
area children
8
income
6
differences
5
brain
5
income associated
4
differences income
4
small differences
4
associated large
4
developing individuals
4
families income
4
higher income
4
children higher
4
families small
4
large differences
4
lower income
4
brain surface
4

References

(Supplied by CrossRef)

MR Rosenzweig et al.
Dev. Neuropsychol. 2003

ER Sowell et al.
Nat. Neurosci. 2003

VC McLoyd et al.
Am. Psychol. 1998

J Brooks-Gunn et al.
Future Child. 1997

DA Hackman et al.
Trends Cogn. Sci. 2009

KG Noble et al.
Dev. Sci. 2006

RD Raizada et al.
Neuroimage 2008

C Stevens et al.
Dev. Sci. 2009

MA Sheridan et al.
PLoS ONE 2012

P Tomalski et al.
Dev. Sci. 2013

P Kim et al.
Proc. Natl. Acad. Sci. USA 2013

Similar Publications