BMC Biophys 2015 25;8. Epub 2015 Feb 25.
Centre for Chromosome Biology, School of Life Sciences, National University of Ireland Galway, Galway, Ireland.
Download full-text PDF
Phys Rep 2014 Oct;543(1):1-60
Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA-19104.
Biological membranes constitute boundaries of cells and cell organelles. These membranes are soft fluid interfaces whose thermodynamic states are dictated by bending moduli, induced curvature fields, and thermal fluctuations. Recently, there has been a flood of experimental evidence highlighting active roles for these structures in many cellular processes ranging from trafficking of cargo to cell motility. Read More
Curr Opin Microbiol 2013 Apr 17;16(2):177-83. Epub 2013 Apr 17.
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, United States.
Recent studies have identified a growing number of mesoscale protein assemblies in both bacterial and eukaryotic cells. Traditionally, these polymeric assemblies are thought to provide structural support for the cell and thus have been classified as the cytoskeleton. However a new class of macromolecular structure is emerging as an organizer of cellular processes that occur on scales hundreds of times larger than a single protein. Read More
Phys Rev Lett 2015 May 6;114(18):188302. Epub 2015 May 6.
Institute of Physical Chemistry, Polish Academy of Sciences ul. Kasprzaka 44/52, 01-224 Warsaw, Poland.
We report three-dimensional structures--mesoscale "atoms"--comprising up to N=8 aqueous droplets compressed in a liquid shell. In contrast to hard colloids that self-assemble into structures unique for a given N, we observe multiple metastable states. We attribute this unexpected richness of metastable structures to the deformability of the cores that introduces irreducible many-body interactions between the droplets. Read More