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Adv Cancer Res 2022 24;156:1-37. Epub 2022 Feb 24.

Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States. Electronic address:

Hepatocellular carcinoma (HCC) risk prediction is increasingly important because of the low annual HCC incidence in patients with the rapidly emerging non-alcoholic fatty liver disease or cured HCV infection. To date, numerous clinical HCC risk biomarkers and scores have been reported in literature. However, heterogeneity in clinico-epidemiological context, e. Read More

J Clin Med 2022 Aug 4;11(15). Epub 2022 Aug 4.

Obstetrical-Gynecological Ultrasound Unit, Department of Obstetrics and Gynecology, Sant'Anna Hospital, 10126 Turin, Italy.

Background And Objectives: The study aimed to evaluate the ability defining the risk of developing preeclampsia by a screening test carried out in the first trimester (between 11 + 0 and 13 + 6 weeks of gestational age), in order to identify high-risk women requiring more intensive health surveillance. The secondary objective was to evaluate the ability of this test to predict the risk of adverse obstetric outcomes such as fetal growth restriction, intrauterine fetal death, gestational hypertension, HELLP syndrome, placental abruption, and preterm birth.

Materials And Methods: This was a single-center study, conducted at the Operative Unit of Obstetrics of the State Hospital of the Republic of San Marino. Read More

Int J Environ Res Public Health 2022 Aug 2;19(15). Epub 2022 Aug 2.

Laboratory for Human Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA.

Determining interventions to combat disease often requires complex analyses of spatial-temporal data to improve health outcomes. For some vulnerable populations, obtaining sufficient data for related analyses is especially difficult, thus exacerbating related healthcare, research, and public health efforts. In the United States (U. Read More

J Natl Compr Canc Netw 2022 Aug;20(8):906-914.e10

1Department of Gynecologic Oncology, Women's Hospital, Zhejiang University School of Medicine.

Background: We sought to identify the absolute risk of specific HPV genotype for cervical intraepithelial neoplasia grade 2/3 or worse (CIN2+/3+) and to develop a risk-based management strategy in an HPV-positive population.

Methods: HPV genotyping was performed based on a 3-year cervical cancer screening cohort. The study endpoints were histologic CIN2+/3+. Read More

Front Oncol 2022 20;12:925596. Epub 2022 Jul 20.

Department of Radiology, Mayo Clinic, Rochester, MN, United States.

Background: Exposure to recurrent infections in childhood was linked to an increased risk of cancer in adulthood. There is also evidence that a history of tonsillectomy, a procedure often performed in children with recurrent infections, is linked to an increased risk of leukemia and Hodgkin lymphoma. Tonsillectomy could be directly associated with cancer risk, or it could be a proxy for another risk factor such as recurrent infections and chronic inflammation. Read More