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Is There a Role for Active Surveillance in Low-Risk Prostate Cancer?

Authors:
Herbert Augustin Katrin Mayerhofer Maximilian Seles Karl Pummer

Urol Int 2015 17;95(2):125-31. Epub 2015 Mar 17.

Department of Urology, Medical University of Graz, Graz, Austria.

Background: Active surveillance (AS) represents an expectant treatment strategy for clinically localized prostate cancer (PCa) with low-risk features.

Objective: The actual management as well as the pros and cons of AS were evaluated.

Methods: A systematic review of the recent literature was performed using the Medline databases.

Conclusions: Since a substantial number of men die with rather than from PCa, there is a considerable role for AS in carefully selected men. AS may also represent a strategy to reduce the burden of overtreatment rooted in intensified PSA testing. Facing the imprecision of risk stratification based on transrectal ultrasound-guided biopsy, accurate clinical staging represents a major medical challenge. Counseling and care require empathy as well as a profound understanding of the biology and the natural history of PCa.

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http://dx.doi.org/10.1159/000371895DOI Listing
June 2016

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