Cardiothoracic ratio for prediction of left ventricular dilation: a systematic review and pooled analysis.

Future Cardiol 2015 Mar;11(2):171-5

Department of Pediatric Cardiology, Children's Hospital of Wisconsin/Medical College of Wisconsin, Milwaukee, WI, USA.

Increased cardiothoracic ratio noted on chest radiographs often prompts concern and further evaluation with additional imaging. This study pools available data assessing the utility of cardiothoracic ratio in predicting left ventricular dilation. A systematic review of the literature was conducted to identify studies comparing cardiothoracic ratio by chest x-ray to left ventricular dilation by echocardiography. Electronic databases were used to identify studies which were then assessed for quality and bias, with those with adequate quality and minimal bias ultimately being included in the pooled analysis. The pooled data were used to determine the sensitivity, specificity, positive predictive value and negative predictive value of cardiomegaly in predicting left ventricular dilation. A total of six studies consisting of 466 patients were included in this analysis. Cardiothoracic ratio had 83.3% sensitivity, 45.4% specificity, 43.5% positive predictive value and 82.7% negative predictive value. When a secondary analysis was conducted with a pediatric study excluded, a total of five studies consisting of 371 patients were included. Cardiothoracic ratio had 86.2% sensitivity, 25.2% specificity, 42.5% positive predictive value and 74.0% negative predictive value. Cardiothoracic ratio as determined by chest radiograph is sensitive but not specific for identifying left ventricular dilation. Cardiothoracic ratio also has a strong negative predictive value for identifying left ventricular dilation.

Download full-text PDF

Source
https://www.futuremedicine.com/doi/10.2217/fca.15.5
Publisher Site
http://dx.doi.org/10.2217/fca.15.5DOI Listing
March 2015
14 Reads

Publication Analysis

Top Keywords

cardiothoracic ratio
32
left ventricular
24
ventricular dilation
24
negative predictive
16
positive predictive
12
pooled analysis
8
ratio chest
8
patients included
8
studies consisting
8
total studies
8
identify studies
8
systematic review
8
predicting left
8
identifying left
8
dilation systematic
8
cardiothoracic
8
predictive
7
ratio
7
left
6
ventricular
6

References

(Supplied by CrossRef)

Díaz Arrieta G et al.
Arch. Cardiol. Mex. 2006

Kadhum AA et al.
Med. J. Basrah Univ. 2007

Pereira-Barretto AC et al.
Rev. Hosp. Clin. Fac. Med. Sao Paulo 1983

Potter JF et al.
J. Am. Geriatr. Soc. 1982

Similar Publications