Pediatr Rev 2015 Mar;36(3):e8-10
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
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Intern Med J 2013 Dec;43(12):1349-50
Division of Dermatology, University Medicine Cluster, National University Hospital, Singapore.
Pediatr Dermatol 2014 Jan-Feb;31(1):e26-7. Epub 2013 Sep 9.
Division of Dermatology, Department of Specialized, Experimental and Diagnostic Medicine, University of Bologna, Bologna, Italy.
Photo-onycholysis caused by doxycycline has rarely been reported in children. We present the case of a boy who loved to play pinball while at the beach, holding tightly to the machine. He developed a photo-onycholysis predominantly on his thumbs while he was being treated with 20 mg/day of doxycycline, a low dose but enough to trigger the photoreaction. Read More
Ned Tijdschr Geneeskd 2013 ;157(27):A6429
Maasstad Ziekenhuis, afd. Dermatologie, Rotterdam, the Netherlands.
A 12-year-old boy consulted the dermatologist for nail abnormalities. Three weeks earlier, he was treated with doxycycline 100 mg BID for 10 days because of erythema chronicum migrans. Following sun exposure, the patient had developed distal onycholysis surrounded by a hyperpigmented zone. Read More
Ugeskr Laeger 2011 Feb;173(9):661-2
Dermato-venerologisk Afdeling, Bispebjerg Hospital, Denmark.
We present two cases of phototoxic onycholysis secondary to doxycycline treatment as malaria prophylaxis. Onycholysis is a rare side-effect to treatment with doxycycline and other tetracyclines. Some physicians are unaware of this risk. Read More