Pediatr Rev 2015 Mar;36(3):e8-10
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
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Qual Life Res 2018 May 14. Epub 2018 May 14.
Department of Social Work, The Chinese University of Hong Kong, Hong Kong, China.
Purpose: In studying health inequality, poverty as measured by income is frequently used; however, this omits the aspects of non-monetary resources and social barriers to achieving improved living standard. Therefore, our study aimed to examine the associations of individual-level deprivation of material and social necessities with general physical and mental health beyond that of income poverty.
Methods: A territory-wide two-stage stratified random sample of 2282 community-dwelling Hong Kong adults was surveyed between 2014 and 2015. Read More
J Expo Sci Environ Epidemiol 2018 Jun 21;28(4):328-336. Epub 2017 Dec 21.
King Edward Memorial Hospital Research Center, Pune, Maharashtra, India.
There is growing evidence that air pollution is associated with increased risk of type 2 diabetes (T2DM). However, information related to whether particulate matter (PM) contributing to worsened metabolic control in T2DM patients is inconsistent. We examined the association of PM exposure with glucose-function parameters in young-onset T2DM patients. Read More
BMC Infect Dis 2017 02 13;17(1):142. Epub 2017 Feb 13.
Department of Chemical Pathology, University of Zimbabwe, College of Health Sciences, P.O. Box A178, Avondale, Harare, Zimbabwe.
Background: There is paucity data on the association of vitamin D deficiency (VDD) and active tuberculosis (TB) in southern Africa where the human immunodeficiency virus (HIV) is co-endemic. We examined the association of serum vitamin D concentrations with active pulmonary tuberculosis (PTB) in HIV-infected (n = 284) and uninfected (n = 267) Black Zimbabweans, in Harare, Zimbabwe.
Methods: We conducted a cross-sectional study of 551 participants comprising 145 HIV/PTB , 139 HIV/PTB, 134 HIV/PTB and 133 HIV/PTB. Read More
BMC Pediatr 2016 05 14;16:66. Epub 2016 May 14.
Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal.
Background: Phenytoin, mainly metabolized by cytochrome P450 enzyme system, has a narrow therapeutic index and may have adverse effects due to inter-individual variation in the dose requirement and genetic polymorphisms. This cross-sectional study was done to study the prevalence of cytochrome P450 CYP2C9 polymorphisms in Indian epileptic children and to see the effect of polymorphisms on serum levels in epileptic children on phenytoin monotherapy.
Methods: We studied 89 epileptic children of North Indian population, randomly selected, to see the genotypic and allelic frequency of CYP2C9 and its association with drug levels on phenytoin monotherapy. Read More
Ann Emerg Med 2015 Mar 14;65(3):318-24. Epub 2014 Aug 14.
Centro Nacional de Investigaciones Cardiovasculares CNIC, Madrid; Hospital Clínico San Carlos, Madrid. Electronic address:
Study Objective: We seek to examine the efficacy and safety of prereperfusion emergency medical services (EMS)-administered intravenous metoprolol in anterior ST-segment elevation myocardial infarction patients undergoing eventual primary angioplasty.
Methods: This is a prespecified subgroup analysis of the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction trial population, who all eventually received oral metoprolol within 12 to 24 hours. We studied patients receiving intravenous metoprolol by EMS and compared them with others treated by EMS but not receiving intravenous metoprolol. Read More