Search our Database of Scientific Publications and Authors

I’m looking for a

    Details and Download Full Text PDF:
    What is important in being cured from: does discordance between physicians and patients matter? (2).

    J Affect Disord 2015 Mar 10;174:372-7. Epub 2014 Dec 10.
    University Department of Psychiatry and Medical Psychology, Unit for Suicide Research, University of Ghent Hospital, Ghent, Belgium.
    Aims: The influence of discordance in what is important in being cured from depression on clinical outcome at 6 months, assessed with a divergence index.

    Methods: 304 outpatients treated for depression by general practitioners or by psychiatrists and completing a 6-month treatment period: a divergence index (divergence between physician and patient view on what is important in being cured from depression) was calculated for each physician-patient pair. The relation between this index and outcome at 6 months was analyzed (including depressive, anxious and somatic symptom severity, positive effect, functional impairment and quality of life (psychological and social relations).

    Results: Response rates (50% improvement) were 65.9% for depressive symptomatology and 46.2% for anxious symptomatology. The subgroup with a poor physician-patient agreement (highest quartile) on expectations had a worse clinical outcome than the subgroup with an excellent physician-patient agreement (lowest quartile): differences in response rate between these groups ranged from 9% to 27%; this difference reached statistical significance for 3 outcome variables (anxiety, positive effect and social relationships).

    Conclusions: The study shows that outcomes with standard antidepressant drugs are still suboptimal and that discordance between what patients׳ and physicians׳ consider important in the definition of cure from depression significantly influences clinical outcomes at 6 months.
    PDF Download - Full Text Link
    ( Please be advised that this article is hosted on an external website not affiliated with
    Source Status ListingPossible

    Similar Publications

    What is important in being cured from depression? Discordance between physicians and patients (1).
    J Affect Disord 2015 Mar 10;174:390-6. Epub 2014 Dec 10.
    University Department of Psychiatry and Medical Psychology, Unit for Suicide Research, University of Ghent Hospital, Ghent, Belgium.
    Aims: The comparison of what physicians and patients consider important in being cured from depression.

    Methods: 426 outpatients (in primary care and in psychiatric care) with a clinical diagnosis of major depression were included: at the start of antidepressant treatment, the importance of a range of items for being cured from depression (depressive, anxious and somatic symptoms, positive affect, functional impairment, quality of life) was assessed in physicians and patients separately and a ranking was made; after 3 months of treatment, the importance of these items for being cured from depression was re-assessed in the patients.

    Results: The items ranked top 10 by physicians mainly contain depressive symptoms while those ranked top 10 by patients mainly contain positive affect items and this attention to positive affect even increases at 3 months follow-up and is higher in patients with recurrent depression than in patients with a first episode of depression. Read More
    Do general practitioners and psychiatrists agree about defining cure from depression? The DEsCRIBE™ survey.
    BMC Psychiatry 2011 Oct 14;11:169. Epub 2011 Oct 14.
    University Psychiatric Centre, Catholic University of Leuven, Campus Gasthuisberg, B-3000 Leuven, Belgium.
    Background: This study aimed to document the outcome dimensions that physicians see as important in defining cure from depression. The study also aimed to analyse physicians' attitudes about depression and to find out whether they affect their prescribing practices and/or the outcome dimensions that they view as important in defining cure.

    Methods: A 51-item questionnaire based on six validated scales was used to rate the importance of several depression outcome dimensions. Read More
    [Results of the French cohort of the European observational study FINDER: quality of life of patients treated with antidepressants].
    Encephale 2013 Apr 22;39(2):101-8. Epub 2012 Aug 22.
    Unité de psychiatrie, Hôtel-Dieu, 1, place du Parvis-Notre-Dame, 75181 Paris cedex 4, France.
    Objectives: To describe health-related quality of life (HRQoL), pain, clinical outcomes and treatment patterns in French patients with depression treated by general practitioners and psychiatrists.

    Methods: Factors Influencing Depression Endpoints Research (FINDER) is a European longitudinal observational, naturalistic, multicentre study to determine the HRQoL (SF-36 and EQ-5D) and to assess outcomes of depression and anxiety (Hospital Anxiety and Depression Scale [HADS]), and pain (VAS) in a population of depressed patients initiating antidepressant treatment. Clinical diagnosis of depression was based on physician's clinical judgment. Read More
    Improving treatment of late life depression in primary care: a randomized clinical trial.
    J Am Geriatr Soc 1994 Aug;42(8):839-46
    Department of Medicine, Indiana University School of Medicine, Regenstrief Institute for Health Care, Indianapolis 46202-2859.
    Objective: Facilitate primary care physicians' compliance with recommended standards of care for late life depression by reducing barriers to recognition and treatment.

    Design: Randomized controlled clinical trial of physician-targeted interventions.

    Setting: Academic primary care group practice caring for an urban, medically indigent patient population. Read More